Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 24352..24977 Replicon plasmid unnamed1
Accession NZ_CP104367
Organism Salmonella enterica subsp. enterica serovar Typhimurium strain PNUSAS028809

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N4533_RS23805 Protein ID WP_000911322.1
Coordinates 24579..24977 (+) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N4533_RS23800 Protein ID WP_000450265.1
Coordinates 24352..24579 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N4533_RS23800 (N4533_23800) 24352..24579 + 228 WP_000450265.1 toxin-antitoxin system antitoxin VapB Antitoxin
N4533_RS23805 (N4533_23805) 24579..24977 + 399 WP_000911322.1 type II toxin-antitoxin system VapC family toxin Toxin
N4533_RS23810 (N4533_23810) 24986..27148 - 2163 WP_000009318.1 type IV conjugative transfer system coupling protein TraD -
N4533_RS23815 (N4533_23815) 27525..28256 - 732 WP_000782438.1 conjugal transfer complement resistance protein TraT -
N4533_RS23820 (N4533_23820) 28292..28786 - 495 WP_010999946.1 entry exclusion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - pefB / pefA / pefC / pefD / rck / spvB / spvC / fdeC 1..93844 93844


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(7-51)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14887.13 Da        Isoelectric Point: 8.5264

>T257793 WP_000911322.1 NZ_CP104367:24579-24977 [Salmonella enterica subsp. enterica serovar Typhimurium]
MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELIYGAEKSQMPERNLAVIEGFVSRLDVLDYDTPAATHT
GQIRAELARQGRPVGPFDQMIAGHARSRGLIVVTNNTREFERVGGLRTEDWS

Download         Length: 399 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8509.49 Da        Isoelectric Point: 4.5358

>AT257793 WP_000450265.1 NZ_CP104367:24352-24579 [Salmonella enterica subsp. enterica serovar Typhimurium]
METSVFLSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAGESWDEWFDGNNVSADFMDNREQPSVQERESF

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References