25766

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 744755..745357 Replicon chromosome
Accession NC_016622
Organism Azospirillum lipoferum 4B

Toxin (Protein)


Gene name PumA Uniprot ID G7Z9L1
Locus tag AZOLI_RS03400 Protein ID WP_014247178.1
Coordinates 744755..745045 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G7Z9L2
Locus tag AZOLI_RS03405 Protein ID WP_014247179.1
Coordinates 745073..745357 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AZOLI_RS03385 740218..742269 + 2052 WP_014247176.1 molybdopterin oxidoreductase family protein -
AZOLI_RS03390 742551..744347 + 1797 WP_014247177.1 single-stranded-DNA-specific exonuclease RecJ -
AZOLI_RS03400 744755..745045 + 291 WP_014247178.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AZOLI_RS03405 745073..745357 + 285 WP_014247179.1 putative addiction module antidote protein Antitoxin
AZOLI_RS03410 745411..746418 + 1008 WP_014247180.1 tRNA dihydrouridine(20/20a) synthase DusA -
AZOLI_RS03415 746464..748566 - 2103 WP_014247181.1 HAMP domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-93)

Antitoxin

Uncharacterized protein HI1420

(6-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10927.51 Da        Isoelectric Point: 9.6893

>T25766 WP_014247178.1 NC_016622:744755-745045 [Azospirillum lipoferum 4B]
MIEIRQTDRFAAWIESLRDDRARMRIEVRIRRLQLGNPGDTKPVGEGVSELRIDYGPGYRVYFIQRGDTLIVLLAGGDKR
SQDRDIAAAIALARDL

Download         Length: 291 bp

>T25766 NC_016622:744755-745045 [Azospirillum lipoferum 4B]
ATGATCGAGATCCGCCAGACCGACCGCTTCGCCGCTTGGATAGAGAGCTTGCGGGATGATCGGGCTCGCATGCGGATCGA
AGTGCGCATCCGCCGGCTTCAGCTCGGCAATCCCGGCGACACGAAGCCGGTGGGCGAGGGGGTCAGCGAACTGCGCATCG
ATTACGGCCCCGGTTACCGCGTCTATTTCATCCAGCGCGGCGACACGCTGATCGTGCTGCTGGCCGGCGGAGACAAGCGG
TCCCAGGACCGCGACATCGCCGCCGCCATCGCGCTGGCGCGGGACCTCTAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10081.49 Da        Isoelectric Point: 4.5600

>AT25766 WP_014247179.1 NC_016622:745073-745357 [Azospirillum lipoferum 4B]
MGRTETRPWDIVDSLDSDERIAAYLDAVLEDGDPQLIVAALGDIARAKGMTEVARNAGLGRQSLYKALSPDGNPEFATVL
KVIKSLGLRLTVSP

Download         Length: 285 bp

>AT25766 NC_016622:745073-745357 [Azospirillum lipoferum 4B]
ATGGGCCGAACCGAGACCCGTCCCTGGGACATCGTCGACAGCCTGGACAGTGACGAGCGCATCGCCGCCTATCTGGATGC
GGTGCTGGAGGATGGCGATCCGCAACTGATCGTCGCGGCGCTCGGCGACATCGCCCGCGCAAAGGGGATGACGGAGGTCG
CTCGCAACGCCGGGCTCGGCCGCCAAAGCCTCTACAAGGCGCTGTCACCGGACGGCAACCCGGAATTCGCCACTGTCCTG
AAGGTGATCAAGTCTCTCGGACTTCGCCTGACCGTCAGTCCATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB G7Z9L1

Antitoxin

Source ID Structure
AlphaFold DB G7Z9L2

References