Detailed information of TA system TA025765

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 2674667..2675360
• Replicon: chromosome
• Accession: NC_016616
• Organism: Dechlorosoma suillum PS

Toxin (Protein)

• Gene name: tad
• Uniprot ID: G8QN36
• Locus tag: DSUI_RS12305
• Protein ID: WP_014237559.1
• Coordinates: 2674983..2675360 (-)
• Length: 126 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: G8QN35
• Locus tag: DSUI_RS12300
• Protein ID: WP_014237558.1
• Coordinates: 2674667..2675002 (-)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
DSUI_RS18730	2671305..2671592	+	288	WP_157870625.1	hypothetical protein	-
DSUI_RS18920	2671720..2671860	+	141	WP_162097136.1	hypothetical protein	-
DSUI_RS12285	2671915..2672661	+	747	WP_014237554.1	flagellar basal-body rod protein FlgF	-
DSUI_RS12290	2672747..2673724	+	978	WP_043799299.1	cysteine synthase A	-
DSUI_RS12295	2674075..2674611	-	537	WP_043799300.1	hypothetical protein	-
DSUI_RS12300	2674667..2675002	-	336	WP_014237558.1	helix-turn-helix domain-containing protein	Antitoxin
DSUI_RS12305	2674983..2675360	-	378	WP_014237559.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
DSUI_RS12310	2675552..2676145	+	594	WP_014237560.1	recombinase family protein	-
DSUI_RS12315	2676142..2679174	+	3033	WP_014237561.1	Tn3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2639455..2676145	36690

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (16-109)

Antitoxin

• Cro/C1-type helix-turn-helix domain (40-93)

Sequences

Toxin

Protein

• Length: 126 a.a.
• Molecular weight: 13764.84 Da
• Isoelectric Point: 8.0053

>T25765 WP_014237559.1 NC_016616:c2675360-2674983 [Azospira oryzae PS]
MADNEKPLEWIASSYKDLMALPPDVRRRFGYALSLAQMGDQDDAAKVLKGYGGAGVLEVVEDDVGGTYRAVYTVKFAEAV
FVLHCFQKKSKSGIATPKVDMDIIRARLKVAEAMAQELRNGKTNH

Nucleotide

• Length: 378 bp

>T25765 NC_016616:c2675360-2674983 [Azospira oryzae PS]
ATGGCCGACAACGAAAAACCGCTCGAATGGATCGCGAGCAGCTACAAGGATCTGATGGCGTTGCCGCCCGACGTGCGTCG
GCGTTTCGGTTACGCGCTGTCGCTAGCCCAGATGGGCGACCAGGACGACGCGGCCAAAGTGCTCAAGGGCTACGGCGGGG
CCGGCGTGCTGGAGGTCGTCGAAGACGATGTCGGTGGCACGTACCGGGCGGTCTACACGGTGAAGTTCGCGGAAGCGGTA
TTCGTCCTGCACTGCTTCCAGAAGAAGAGCAAGAGCGGGATCGCCACGCCCAAGGTGGACATGGACATCATCCGCGCTCG
GCTGAAGGTGGCCGAGGCAATGGCACAGGAGTTACGAAATGGAAAAACGAATCATTGA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12199.37 Da
• Isoelectric Point: 10.0996

>AT25765 WP_014237558.1 NC_016616:c2675002-2674667 [Azospira oryzae PS]
MEKRIIEGVEVQRSSGNVFADLGLPDAEKLKIKTGLVIEIRKAMRALSLTQQAAAKRMGIPQPKVSGMMHGDFTNLSERK
LMDCLNRLGYDIEIKVRPAAEPIGHLTLATA

Nucleotide

• Length: 336 bp

>AT25765 NC_016616:c2675002-2674667 [Azospira oryzae PS]
ATGGAAAAACGAATCATTGAAGGCGTCGAGGTTCAACGCAGCTCGGGCAACGTCTTCGCCGACCTGGGACTGCCCGACGC
CGAAAAGCTGAAGATCAAAACTGGCCTGGTAATCGAGATCAGGAAGGCGATGCGCGCCCTGAGCCTGACGCAACAAGCGG
CGGCCAAGCGCATGGGCATCCCGCAACCGAAGGTATCGGGCATGATGCATGGCGACTTCACCAACCTGTCCGAGCGCAAG
CTGATGGACTGCCTGAATCGCCTGGGCTACGACATCGAAATCAAGGTGCGACCGGCGGCCGAGCCGATTGGGCACCTGAC
GCTTGCTACCGCCTGA

Structures

Toxin

• AlphaFold DB: G8QN36

Antitoxin

• AlphaFold DB: G8QN35