Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1956426..1956697 Replicon chromosome
Accession NZ_CP104328
Organism Escherichia coli strain THB42-F2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1956556..1956659 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1956426..1956697 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0499_RS09355 1952981..1953643 - 663 WP_000944256.1 exodeoxyribonuclease X -
N0499_RS09360 1953667..1954323 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
N0499_RS09365 1954425..1954655 - 231 WP_000916763.1 DNA polymerase III subunit theta -
N0499_RS09370 1954794..1955168 + 375 WP_000168747.1 CopC domain-containing protein YobA -
N0499_RS09375 1955172..1956044 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
N0499_RS09380 1956057..1956398 + 342 WP_000976476.1 YebY family protein -
- 1956426..1956697 - 272 - - Antitoxin
- 1956556..1956659 + 104 - - Toxin
N0499_RS09385 1956794..1957450 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
N0499_RS09390 1957451..1957642 - 192 WP_000457842.1 YebW family protein -
N0499_RS09395 1957747..1957983 - 237 WP_001295499.1 YebV family protein -
N0499_RS09400 1958101..1959540 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T257626 NZ_CP104328:1956556-1956659 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT257626 NZ_CP104328:c1956697-1956426 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References