Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 292143..292803 Replicon chromosome
Accession NZ_CP104323
Organism Stenotrophomonas maltophilia strain ACYCc.3B

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag K7564_RS01345 Protein ID WP_227863872.1
Coordinates 292143..292442 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag K7564_RS01350 Protein ID WP_005420598.1
Coordinates 292501..292803 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7564_RS01320 (K7564_01320) 287859..288140 + 282 WP_227863867.1 hypothetical protein -
K7564_RS01325 (K7564_01325) 288238..288738 - 501 WP_227863868.1 hypothetical protein -
K7564_RS01330 (K7564_01330) 288735..289802 - 1068 WP_227863869.1 AAA family ATPase -
K7564_RS01335 (K7564_01335) 289925..290440 + 516 WP_227863870.1 hypothetical protein -
K7564_RS01340 (K7564_01340) 290532..291719 - 1188 WP_227863871.1 integrase arm-type DNA-binding domain-containing protein -
K7564_RS01345 (K7564_01345) 292143..292442 + 300 WP_227863872.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7564_RS01350 (K7564_01350) 292501..292803 + 303 WP_005420598.1 putative addiction module antidote protein Antitoxin
K7564_RS01355 (K7564_01355) 292976..293377 - 402 WP_126411622.1 hypothetical protein -
K7564_RS01360 (K7564_01360) 293985..294755 + 771 WP_227863873.1 DUF3011 domain-containing protein -
K7564_RS01365 (K7564_01365) 294827..295276 - 450 WP_227863874.1 hypothetical protein -
K7564_RS01370 (K7564_01370) 295552..296472 + 921 WP_227863875.1 arginase -
K7564_RS01375 (K7564_01375) 296633..296770 + 138 WP_014035659.1 entericidin A/B family lipoprotein -
K7564_RS01380 (K7564_01380) 296974..297195 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 247622..295276 47654


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(2-99)

Antitoxin

Uncharacterized protein HI1420

(8-97)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11202.96 Da        Isoelectric Point: 10.6580

>T257583 WP_227863872.1 NZ_CP104323:292143-292442 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARILARIGRLAEGHPGDHRYLGDGISELRIDAGPGYRLYYTQCGRQLLILLVGG
DKSSQQRDIEKAREIARAL

Download         Length: 300 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10764.36 Da        Isoelectric Point: 8.0360

>AT257583 WP_005420598.1 NZ_CP104323:292501-292803 [Stenotrophomonas maltophilia]
MAIKRKVELKSFDVAEHLRTPEEMAAYLDACIEESEGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FATILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References