Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2141818..2142089 Replicon chromosome
Accession NZ_CP104309
Organism Escherichia coli O157:H7 strain 380-94

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2141948..2142051 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2141818..2142089 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NUE46_RS10650 2138373..2139035 - 663 WP_000944243.1 exodeoxyribonuclease X -
NUE46_RS10655 2139059..2139715 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein YobB -
NUE46_RS10660 2139817..2140047 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NUE46_RS10665 2140186..2140560 + 375 WP_000168751.1 CopC domain-containing protein YobA -
NUE46_RS10670 2140564..2141436 + 873 WP_000879314.1 copper homeostasis membrane protein CopD -
NUE46_RS10675 2141449..2141790 + 342 WP_000976483.1 YebY family protein -
- 2141818..2142089 - 272 - - Antitoxin
- 2141948..2142051 + 104 - - Toxin
NUE46_RS10680 2142186..2142842 + 657 WP_000812736.1 protein-serine/threonine phosphatase -
NUE46_RS10685 2142843..2143034 - 192 WP_001296140.1 YebW family protein -
NUE46_RS10690 2143139..2143375 - 237 WP_001295499.1 YebV family protein -
NUE46_RS10695 2143493..2144932 - 1440 WP_001302304.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T257535 NZ_CP104309:2141948-2142051 [Escherichia coli O157:H7]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT257535 NZ_CP104309:c2142089-2141818 [Escherichia coli O157:H7]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References