Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 2505525..2506054 Replicon chromosome
Accession NZ_CP104302
Organism Mycolicibacterium brumae strain ATCC 51384

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Z93_RS12165 Protein ID WP_090593452.1
Coordinates 2505525..2505782 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Z93_RS12170 Protein ID WP_090593455.1
Coordinates 2505779..2506054 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Z93_RS12145 (L2Z93_002423) 2500618..2501586 - 969 WP_234785976.1 bifunctional oligoribonuclease/PAP phosphatase NrnA -
L2Z93_RS12150 (L2Z93_002424) 2501570..2502040 - 471 WP_090585273.1 30S ribosome-binding factor RbfA -
L2Z93_RS12155 (L2Z93_002425) 2502076..2504808 - 2733 WP_260575402.1 translation initiation factor IF-2 -
L2Z93_RS12160 (L2Z93_002426) 2504886..2505242 - 357 WP_090593449.1 YlxR family protein -
L2Z93_RS12165 (L2Z93_002427) 2505525..2505782 - 258 WP_090593452.1 Txe/YoeB family addiction module toxin Toxin
L2Z93_RS12170 (L2Z93_002428) 2505779..2506054 - 276 WP_090593455.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L2Z93_RS12175 (L2Z93_002429) 2506141..2507139 - 999 WP_090593458.1 transcription termination factor NusA -
L2Z93_RS12180 (L2Z93_002430) 2507136..2507705 - 570 WP_090593462.1 ribosome maturation factor RimP -
L2Z93_RS12185 (L2Z93_002431) 2507832..2508353 + 522 WP_090593542.1 hypothetical protein -
L2Z93_RS12190 (L2Z93_002432) 2508350..2508931 + 582 WP_090593465.1 ferritin-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-72)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10086.48 Da        Isoelectric Point: 9.4804

>T257521 WP_090593452.1 NZ_CP104302:c2505782-2505525 [Mycolicibacterium brumae]
MRSVSFDPDGWEDFLHWLATDRKIARRITRLIGEIQRDPFAGIGKPEPLKGELSGYWSRRIDDEHRLVYRADATEVKILK
ARYHY

Download         Length: 258 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10029.24 Da        Isoelectric Point: 4.6413

>AT257521 WP_090593455.1 NZ_CP104302:c2506054-2505779 [Mycolicibacterium brumae]
MSISASEARQRLFPLLEQVNVDHEPVRITSKAGDAVLMSADDYDSWQETVYLLRSPENARRLMEAVARDKAGDVGHAVSL
DELRKMAGGAD

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References