Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-Phd
Location 798051..798595 Replicon chromosome
Accession NZ_CP104302
Organism Mycolicibacterium brumae strain ATCC 51384

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L2Z93_RS04120 Protein ID WP_090589258.1
Coordinates 798332..798595 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L2Z93_RS04115 Protein ID WP_090589257.1
Coordinates 798051..798335 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L2Z93_RS04095 (L2Z93_000817) 793756..794322 - 567 WP_090589253.1 lipid droplet-associated protein -
L2Z93_RS04100 (L2Z93_000818) 794404..795405 + 1002 WP_090589254.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -
L2Z93_RS04105 (L2Z93_000819) 795441..796730 - 1290 WP_090589255.1 hypothetical protein -
L2Z93_RS04110 (L2Z93_000820) 796835..797914 + 1080 WP_090589256.1 redox-regulated ATPase YchF -
L2Z93_RS04115 (L2Z93_000821) 798051..798335 + 285 WP_090589257.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L2Z93_RS04120 (L2Z93_000822) 798332..798595 + 264 WP_090589258.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L2Z93_RS04125 (L2Z93_000823) 798558..799064 - 507 WP_090589259.1 SRPBCC domain-containing protein -
L2Z93_RS04130 (L2Z93_000824) 799283..799750 + 468 WP_162561929.1 DUF1877 family protein -
L2Z93_RS04135 (L2Z93_000825) 799779..800171 + 393 WP_090589261.1 type II toxin-antitoxin system VapC family toxin -
L2Z93_RS04140 (L2Z93_000826) 800197..801429 - 1233 WP_272938674.1 alpha-hydroxy acid oxidase -
L2Z93_RS04145 (L2Z93_000827) 801748..802083 + 336 WP_128111804.1 hypothetical protein -
L2Z93_RS04150 (L2Z93_000828) 802096..802653 + 558 WP_090589264.1 VOC family protein -
L2Z93_RS04155 (L2Z93_000829) 802650..803384 + 735 WP_090589265.1 aminoglycoside 3'-phosphotransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(34-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10316.84 Da        Isoelectric Point: 10.2355

>T257513 WP_090589258.1 NZ_CP104302:798332-798595 [Mycolicibacterium brumae]
MTYRVELTRRARRSLSEELPEVVAAACWEFIRGPLAENPHRVGKCLRDELAGRWSARRGDFRVVYEIHENVVVVRVIDVR
HRRDAYR

Download         Length: 264 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10280.63 Da        Isoelectric Point: 4.3604

>AT257513 WP_090589257.1 NZ_CP104302:798051-798335 [Mycolicibacterium brumae]
MTTLPIAEVRANLSKLVDEAVRTHQRVEVTKNGRRAAVLISADDYDSLMETLEILGDREAMDALREADADIAAGRVYPLD
EVEAELRAKGIIGS

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References