Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2906310..2906963 Replicon chromosome
Accession NZ_CP104297
Organism Acinetobacter baumannii strain ZHOU

Toxin (Protein)


Gene name cptA Uniprot ID A0A1S2G112
Locus tag N2K92_RS13735 Protein ID WP_071210859.1
Coordinates 2906310..2906699 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag N2K92_RS13740 Protein ID WP_001288210.1
Coordinates 2906706..2906963 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K92_RS13720 (N2K92_13735) 2901427..2903622 - 2196 WP_071210860.1 TRAP transporter large permease subunit -
N2K92_RS13725 (N2K92_13740) 2903810..2904376 - 567 WP_000651536.1 rhombosortase -
N2K92_RS13730 (N2K92_13745) 2904455..2905540 - 1086 WP_000049106.1 hypothetical protein -
N2K92_RS13735 (N2K92_13750) 2906310..2906699 - 390 WP_071210859.1 hypothetical protein Toxin
N2K92_RS13740 (N2K92_13755) 2906706..2906963 - 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
N2K92_RS13745 (N2K92_13760) 2907151..2908323 + 1173 WP_071210858.1 acyl-CoA dehydrogenase family protein -
N2K92_RS13750 (N2K92_13765) 2908373..2909863 - 1491 WP_016686239.1 NAD(P)/FAD-dependent oxidoreductase -
N2K92_RS13755 (N2K92_13770) 2910045..2910422 - 378 WP_001216380.1 50S ribosomal protein L17 -
N2K92_RS13760 (N2K92_13775) 2910441..2911448 - 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15690.01 Da        Isoelectric Point: 10.4623

>T257501 WP_071210859.1 NZ_CP104297:c2906699-2906310 [Acinetobacter baumannii]
MINHLNFKLKYSRFSIIFQFFIGLSLAVLFYQLMPLLWWLVVISLLFINFIFFLKRPQLAQIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKKLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT257501 WP_001288210.1 NZ_CP104297:c2906963-2906706 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1S2G112

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References