Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 265897..266545 Replicon chromosome
Accession NZ_CP104292
Organism Stenotrophomonas maltophilia strain ACYCe.8N

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag K7573_RS01185 Protein ID WP_165711185.1
Coordinates 265897..266202 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag K7573_RS01190 Protein ID WP_005407703.1
Coordinates 266243..266545 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7573_RS01155 (K7573_01155) 261851..262642 - 792 WP_099523351.1 zinc-dependent peptidase -
K7573_RS01160 (K7573_01160) 262609..262887 - 279 WP_005411956.1 hypothetical protein -
K7573_RS01165 (K7573_01165) 263032..263997 + 966 WP_043035430.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
K7573_RS01170 (K7573_01170) 263994..264725 + 732 WP_005407698.1 type III pantothenate kinase -
K7573_RS01175 (K7573_01175) 264735..265589 + 855 WP_005411958.1 SPOR domain-containing protein -
K7573_RS01185 (K7573_01185) 265897..266202 + 306 WP_165711185.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7573_RS01190 (K7573_01190) 266243..266545 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
K7573_RS01195 (K7573_01195) 266803..267102 - 300 WP_005407704.1 hypothetical protein -
K7573_RS01200 (K7573_01200) 267183..267590 - 408 WP_165711186.1 hypothetical protein -
K7573_RS01205 (K7573_01205) 268185..268955 + 771 WP_005411960.1 DUF3011 domain-containing protein -
K7573_RS01210 (K7573_01210) 268980..269327 - 348 WP_005411961.1 hypothetical protein -
K7573_RS01215 (K7573_01215) 269458..270378 + 921 WP_005407709.1 arginase -
K7573_RS01220 (K7573_01220) 270539..270676 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
K7573_RS01225 (K7573_01225) 270714..270893 - 180 WP_164225318.1 hypothetical protein -
K7573_RS01230 (K7573_01230) 270880..271101 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11372.08 Da        Isoelectric Point: 11.2113

>T257496 WP_165711185.1 NZ_CP104292:265897-266202 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSGLRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT257496 WP_005407703.1 NZ_CP104292:266243-266545 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References