Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 732770..734238 Replicon chromosome
Accession NZ_CP104290
Organism Stenotrophomonas maltophilia strain ACYCa.6E

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag K7574_RS03285 Protein ID WP_172459916.1
Coordinates 732770..733639 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag K7574_RS03290 Protein ID WP_227415337.1
Coordinates 733636..734238 (-) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7574_RS03265 (K7574_03265) 728936..729514 - 579 WP_227415335.1 metal-dependent hydrolase -
K7574_RS03270 (K7574_03270) 729625..729993 - 369 WP_024957270.1 YraN family protein -
K7574_RS03275 (K7574_03275) 729983..731716 - 1734 WP_227415336.1 penicillin-binding protein activator -
K7574_RS03280 (K7574_03280) 731798..732616 + 819 WP_005412235.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
K7574_RS03285 (K7574_03285) 732770..733639 - 870 WP_172459916.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
K7574_RS03290 (K7574_03290) 733636..734238 - 603 WP_227415337.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
K7574_RS03300 (K7574_03300) 734982..735461 - 480 WP_049459440.1 DM13 domain-containing protein -
K7574_RS03305 (K7574_03305) 735779..736531 - 753 WP_227415338.1 NRDE family protein -
K7574_RS03310 (K7574_03310) 736890..737291 + 402 WP_008266948.1 division/cell wall cluster transcriptional repressor MraZ -
K7574_RS03315 (K7574_03315) 737306..738274 + 969 WP_012479154.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
K7574_RS03320 (K7574_03320) 738271..738534 + 264 WP_005412242.1 cell division protein FtsL -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 711993..734238 22245


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(40-268)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-53)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32480.09 Da        Isoelectric Point: 6.0916

>T257494 WP_172459916.1 NZ_CP104290:c733639-732770 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRGTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Download         Length: 870 bp

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 22312.02 Da        Isoelectric Point: 11.0945

>AT257494 WP_227415337.1 NZ_CP104290:c734238-733636 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKHLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Download         Length: 603 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References