Detailed information of TA system TA257494

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 732770..734238
• Replicon: chromosome
• Accession: NZ_CP104290
• Organism: Stenotrophomonas maltophilia strain ACYCa.6E

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: K7574_RS03285
• Protein ID: WP_172459916.1
• Coordinates: 732770..733639 (-)
• Length: 290 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: K7574_RS03290
• Protein ID: WP_227415337.1
• Coordinates: 733636..734238 (-)
• Length: 201 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
K7574_RS03265 (K7574_03265)	728936..729514	-	579	WP_227415335.1	metal-dependent hydrolase	-
K7574_RS03270 (K7574_03270)	729625..729993	-	369	WP_024957270.1	YraN family protein	-
K7574_RS03275 (K7574_03275)	729983..731716	-	1734	WP_227415336.1	penicillin-binding protein activator	-
K7574_RS03280 (K7574_03280)	731798..732616	+	819	WP_005412235.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
K7574_RS03285 (K7574_03285)	732770..733639	-	870	WP_172459916.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
K7574_RS03290 (K7574_03290)	733636..734238	-	603	WP_227415337.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
K7574_RS03300 (K7574_03300)	734982..735461	-	480	WP_049459440.1	DM13 domain-containing protein	-
K7574_RS03305 (K7574_03305)	735779..736531	-	753	WP_227415338.1	NRDE family protein	-
K7574_RS03310 (K7574_03310)	736890..737291	+	402	WP_008266948.1	division/cell wall cluster transcriptional repressor MraZ	-
K7574_RS03315 (K7574_03315)	737306..738274	+	969	WP_012479154.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
K7574_RS03320 (K7574_03320)	738271..738534	+	264	WP_005412242.1	cell division protein FtsL	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	711993..734238	22245

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (40-268)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-53)

Sequences

Toxin

Protein

• Length: 290 a.a.
• Molecular weight: 32480.09 Da
• Isoelectric Point: 6.0916

>T257494 WP_172459916.1 NZ_CP104290:c733639-732770 [Stenotrophomonas maltophilia]
VTHSPPLPQRVASIRQRLLDLARSRGEDFQFVLDRFAVERLLYRLSASRYRDQFLLKGAMLFAVWFDAPHRPTRDADFLR
FGSADPDHLLHIARSLCAIPDDDGLCFDPGSIAIEATREEAEYEGLRIRLTAHLGRSRCHVQWDVGFGDAVTPPPPEIAY
PVMLDGFPLPCLHVYPRETVFAEKLEAIAALGIANSRMKDFFDLLALVREDAMDRPHLVAAIGATFDRRGTPAPPPLPYG
LTQSFAADTQKQTQWRAFLRRNRLIAPDLSSVIAEIADYLDTLDTTVQS

Nucleotide

• Length: 870 bp

Antitoxin

Protein

• Length: 201 a.a.
• Molecular weight: 22312.02 Da
• Isoelectric Point: 11.0945

>AT257494 WP_227415337.1 NZ_CP104290:c734238-733636 [Stenotrophomonas maltophilia]
MGNAEANARKLLRRAGTLRARELVTAGIARAQLTRLVEAGALIRLSRGVYALAERNSDDTDDGLRIIAERLPHPRLCLLS
ALRLHGLTTQAPFERWVSIGNSDRVPRIDWPPLRVVRMSAKTLNAGLEERRVGKHLIYVSNVAKTVVDCFKFRNLVGLDV
AIEALRDALHSRATTPDALMEYARICRVARLMRPYLDALA

Nucleotide

• Length: 603 bp