Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 270307..270955 Replicon chromosome
Accession NZ_CP104288
Organism Stenotrophomonas maltophilia strain ACYCa.2H

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag K7568_RS01205 Protein ID WP_005407702.1
Coordinates 270307..270612 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag K7568_RS01210 Protein ID WP_227860157.1
Coordinates 270653..270955 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
K7568_RS01175 (K7568_01175) 266261..267052 - 792 WP_165931275.1 zinc-dependent peptidase -
K7568_RS01180 (K7568_01180) 267019..267297 - 279 WP_005407696.1 hypothetical protein -
K7568_RS01185 (K7568_01185) 267442..268407 + 966 WP_043035430.1 bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA -
K7568_RS01190 (K7568_01190) 268404..269135 + 732 WP_005407698.1 type III pantothenate kinase -
K7568_RS01195 (K7568_01195) 269145..269999 + 855 WP_005411958.1 SPOR domain-containing protein -
K7568_RS01205 (K7568_01205) 270307..270612 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
K7568_RS01210 (K7568_01210) 270653..270955 + 303 WP_227860157.1 putative addiction module antidote protein Antitoxin
K7568_RS01215 (K7568_01215) 271213..271512 - 300 WP_005407704.1 hypothetical protein -
K7568_RS01220 (K7568_01220) 271593..272000 - 408 WP_043035194.1 hypothetical protein -
K7568_RS01225 (K7568_01225) 272595..273365 + 771 WP_005411960.1 DUF3011 domain-containing protein -
K7568_RS01230 (K7568_01230) 273390..273737 - 348 WP_005411961.1 hypothetical protein -
K7568_RS01235 (K7568_01235) 273868..274788 + 921 WP_005407709.1 arginase -
K7568_RS01240 (K7568_01240) 274949..275086 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
K7568_RS01245 (K7568_01245) 275295..275516 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Uncharacterized protein HI1420

(6-99)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T257490 WP_005407702.1 NZ_CP104288:270307-270612 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10733.30 Da        Isoelectric Point: 7.2780

>AT257490 WP_227860157.1 NZ_CP104288:270653-270955 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARTQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References