Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3802044..3802701 Replicon chromosome
Accession NZ_CP104285
Organism Enterobacter mori strain JT.W3M11

Toxin (Protein)


Gene name cptA Uniprot ID A0A6S5Y1H5
Locus tag N2K86_RS17905 Protein ID WP_010435320.1
Coordinates 3802044..3802454 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V3PWU7
Locus tag N2K86_RS17910 Protein ID WP_010435322.1
Coordinates 3802435..3802701 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K86_RS17885 (N2K86_17885) 3798036..3799769 - 1734 WP_260659500.1 single-stranded-DNA-specific exonuclease RecJ -
N2K86_RS17890 (N2K86_17890) 3799775..3800488 - 714 WP_260659501.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
N2K86_RS17895 (N2K86_17895) 3800517..3801413 - 897 WP_089600303.1 site-specific tyrosine recombinase XerD -
N2K86_RS17900 (N2K86_17900) 3801515..3802036 + 522 WP_260659502.1 flavodoxin FldB -
N2K86_RS17905 (N2K86_17905) 3802044..3802454 - 411 WP_010435320.1 protein YgfX Toxin
N2K86_RS17910 (N2K86_17910) 3802435..3802701 - 267 WP_010435322.1 FAD assembly factor SdhE Antitoxin
N2K86_RS17915 (N2K86_17915) 3802996..3803976 + 981 WP_260659503.1 tRNA-modifying protein YgfZ -
N2K86_RS17920 (N2K86_17920) 3804055..3805188 - 1134 WP_260659428.1 integrase core domain-containing protein -
N2K86_RS17925 (N2K86_17925) 3805385..3806044 - 660 WP_003863433.1 hemolysin III family protein -
N2K86_RS17930 (N2K86_17930) 3806311..3807042 + 732 WP_260661716.1 MurR/RpiR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16173.06 Da        Isoelectric Point: 11.5020

>T257484 WP_010435320.1 NZ_CP104285:c3802454-3802044 [Enterobacter mori]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFVLLMPWPLSYTPLWLLLLSFVVFDSVRSQRRINARQGEIKLLMDSRLRWQGK
EWEIVGTPWMLSVGMMLRLRQPEGGRRQHLWLAADSMDAAEWRDLRRMMLQQPTQD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1340

>AT257484 WP_010435322.1 NZ_CP104285:c3802701-3802435 [Enterobacter mori]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDDDKRLFVRLLESDDPDLFNWLMNHGKPADTELQRMVQLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6S5Y1H5

Antitoxin

Source ID Structure
AlphaFold DB V3PWU7

References