Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2944463..2945053 Replicon chromosome
Accession NZ_CP104285
Organism Enterobacter mori strain JT.W3M11

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag N2K86_RS13960 Protein ID WP_260658984.1
Coordinates 2944463..2944795 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag N2K86_RS13965 Protein ID WP_260658985.1
Coordinates 2944796..2945053 (-) Length 86 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K86_RS13945 (N2K86_13945) 2940627..2941952 + 1326 WP_260658982.1 SidA/IucD/PvdA family monooxygenase -
N2K86_RS13950 (N2K86_13950) 2941979..2944168 + 2190 WP_260658983.1 TonB-dependent siderophore receptor -
N2K86_RS13960 (N2K86_13960) 2944463..2944795 - 333 WP_260658984.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
N2K86_RS13965 (N2K86_13965) 2944796..2945053 - 258 WP_260658985.1 antitoxin Antitoxin
N2K86_RS13970 (N2K86_13970) 2945319..2946278 - 960 WP_260658986.1 zinc-binding alcohol dehydrogenase family protein -
N2K86_RS13975 (N2K86_13975) 2946325..2946714 - 390 WP_260658987.1 RidA family protein -
N2K86_RS13980 (N2K86_13980) 2946856..2947776 + 921 WP_260658988.1 LysR family transcriptional regulator -
N2K86_RS13985 (N2K86_13985) 2947852..2948154 - 303 WP_260658989.1 helix-turn-helix domain-containing protein -
N2K86_RS13990 (N2K86_13990) 2948159..2948512 - 354 WP_062935980.1 type II toxin-antitoxin system RelE/ParE family toxin -
N2K86_RS13995 (N2K86_13995) 2948732..2949682 - 951 WP_010432106.1 HTH-type transcriptional regulator Cbl -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-108)

Antitoxin

(4-84)


Sequences


Toxin        


Download         Length: 111 a.a.        Molecular weight: 11745.68 Da        Isoelectric Point: 7.7230

>T257481 WP_260658984.1 NZ_CP104285:c2944795-2944463 [Enterobacter mori]
MDRGEIWLVSLDPIAGHEQSGKCPVLIVSKALFNKLTRLPVVVPVTSGGNFARTAGFTVSLEGAGTKTTGVICCDQPRTI
DMAARNGMRLERIPDAVVNEVLARLDAILN

Download         Length: 333 bp


Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9392.90 Da        Isoelectric Point: 4.5937

>AT257481 WP_260658985.1 NZ_CP104285:c2945053-2944796 [Enterobacter mori]
MYTTRLKKVGGSIMLAVPPAVLKTLELSTDSEVGMTINNGCLIIEPQKRPHYSLEELLAQCDPHAEMSEEDREWVVAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References