Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 271348..271944 Replicon chromosome
Accession NZ_CP104285
Organism Enterobacter mori strain JT.W3M11

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N2K86_RS01315 Protein ID WP_260660198.1
Coordinates 271642..271944 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N2K86_RS01310 Protein ID WP_041912091.1
Coordinates 271348..271635 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K86_RS01305 (N2K86_01305) 269720..271351 + 1632 WP_260660197.1 Na/Pi cotransporter family protein -
N2K86_RS01310 (N2K86_01310) 271348..271635 - 288 WP_041912091.1 putative addiction module antidote protein Antitoxin
N2K86_RS01315 (N2K86_01315) 271642..271944 - 303 WP_260660198.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2K86_RS01320 (N2K86_01320) 272142..273014 + 873 WP_260660199.1 23S rRNA pseudouridine(2604) synthase RluF -
N2K86_RS01325 (N2K86_01325) 273015..273287 - 273 WP_014830263.1 DUF3811 domain-containing protein -
N2K86_RS01330 (N2K86_01330) 273338..274282 - 945 WP_260660200.1 ketopantoate/pantoate/pantothenate transporter PanS -
N2K86_RS01335 (N2K86_01335) 274376..275725 - 1350 WP_260660201.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-92)

Antitoxin

Uncharacterized protein HI1420

(3-89)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11443.21 Da        Isoelectric Point: 9.7113

>T257475 WP_260660198.1 NZ_CP104285:c271944-271642 [Enterobacter mori]
MKEIVQTESFRRWEQNLKDRRAKTIIASRLFRLANGLAGDVKPVGEGISELRIHFGPGYRIYFKDQSNCIIVLLCGGDKS
SQDRDILMAKMLGNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10143.58 Da        Isoelectric Point: 6.4596

>AT257475 WP_041912091.1 NZ_CP104285:c271635-271348 [Enterobacter mori]
MHKLTPYDPANALVDDEEIAVFIADALETGDSTYIAKALGVVARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGFGLTLKHAGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References