Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 298495..299091 Replicon chromosome
Accession NZ_CP104284
Organism Enterobacter hormaechei subsp. steigerwaltii strain JT.WLB1A

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N2K85_RS01425 Protein ID WP_063136798.1
Coordinates 298789..299091 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID A0A927HL08
Locus tag N2K85_RS01420 Protein ID WP_023295755.1
Coordinates 298495..298782 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K85_RS01415 (N2K85_01415) 296867..298498 + 1632 WP_003860350.1 Na/Pi cotransporter family protein -
N2K85_RS01420 (N2K85_01420) 298495..298782 - 288 WP_023295755.1 putative addiction module antidote protein Antitoxin
N2K85_RS01425 (N2K85_01425) 298789..299091 - 303 WP_063136798.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2K85_RS01430 (N2K85_01430) 299289..300161 + 873 WP_260673248.1 23S rRNA pseudouridine(2604) synthase RluF -
N2K85_RS01435 (N2K85_01435) 300162..300434 - 273 WP_017382612.1 DUF3811 domain-containing protein -
N2K85_RS01440 (N2K85_01440) 300485..301429 - 945 WP_015570166.1 ketopantoate/pantoate/pantothenate transporter PanS -
N2K85_RS01445 (N2K85_01445) 301523..302872 - 1350 WP_006810501.1 lysine-sensitive aspartokinase 3 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-93)

Antitoxin

Uncharacterized protein HI1420

(3-90)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11455.21 Da        Isoelectric Point: 10.3736

>T257459 WP_063136798.1 NZ_CP104284:c299091-298789 [Enterobacter hormaechei subsp. steigerwaltii]
MKEIVQTESFRRWEQNLKDRRTKTIIASRLFRLANGLAGDIRPVGEGISELRIHFGPGYRIYFKDQGNSIIVLLCGGDKS
SQARDILMAKMLSNVSQWQE

Download         Length: 303 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10101.59 Da        Isoelectric Point: 5.7807

>AT257459 WP_023295755.1 NZ_CP104284:c298782-298495 [Enterobacter hormaechei subsp. steigerwaltii]
MHKLTPYDPANALLDDEEIAVFMADALETGDSAYIAKALGVIARAKGMSTISQQTGLSREQLYRSFSDKGNPTLKTTLAV
MKALGLGLTIKPSGD

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References