257458

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3334..3817 Replicon plasmid p2_SCLZS63
Accession NZ_CP104281
Organism Comamonas aquatica strain SCLZS63

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag N2K12_RS19980 Protein ID WP_197577754.1
Coordinates 3334..3606 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag N2K12_RS19985 Protein ID WP_197577755.1
Coordinates 3590..3817 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2K12_RS19965 1217..2194 - 978 WP_260675740.1 replication initiation protein -
N2K12_RS19970 2469..3107 + 639 WP_197577753.1 ParA family partition ATPase -
N2K12_RS19975 3098..3301 + 204 WP_174863008.1 hypothetical protein -
N2K12_RS19980 3334..3606 - 273 WP_197577754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2K12_RS19985 3590..3817 - 228 WP_197577755.1 TraY domain-containing protein Antitoxin
N2K12_RS19990 3993..4403 + 411 WP_197577756.1 fosfomycin resistance glutathione transferase -
N2K12_RS19995 4507..6303 - 1797 WP_260675741.1 MobA/MobL family protein -
N2K12_RS20000 6509..6943 + 435 WP_260675738.1 conjugal transfer protein TraD -
N2K12_RS20005 6940..7176 + 237 WP_174863012.1 hypothetical protein -
N2K12_RS20010 7182..8120 - 939 WP_260675739.1 DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..9512 9512


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-88)

Antitoxin

Relaxosome protein TraY

(3-49)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10427.09 Da        Isoelectric Point: 10.3861

>T257458 WP_197577754.1 NZ_CP104281:c3606-3334 [Comamonas aquatica]
MAWKIELSEGAVKNLKQLDHQHARRILNFLHSRVAQLDDPRSIGEALKGSKLGELWKYRVGDYRIIADIEDSVMRVLVLK
VGNRREVYRG

Download         Length: 273 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8607.86 Da        Isoelectric Point: 4.6258

>AT257458 WP_197577755.1 NZ_CP104281:c3817-3590 [Comamonas aquatica]
MSVSLRLPPELNQRLSLLAEQTGRSKTFYMLEAIKQHLDDLEDVYLAERELEAVRSGKSKAVPLEEVMKQYGLED

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References