Detailed information of TA system TA257457

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1829403..1830901
• Replicon: chromosome
• Accession: NZ_CP104279
• Organism: Comamonas aquatica strain SCLZS63

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: N2K12_RS08735
• Protein ID: WP_260675447.1
• Coordinates: 1829999..1830901 (+)
• Length: 301 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: N2K12_RS08730
• Protein ID: WP_260675446.1
• Coordinates: 1829403..1830002 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
N2K12_RS08725	1827301..1829265	+	1965	WP_260675445.1	DEAD/DEAH box helicase	-
N2K12_RS08730	1829403..1830002	+	600	WP_260675446.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
N2K12_RS08735	1829999..1830901	+	903	WP_260675447.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1811498..1843184	31686

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-258)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (7-52)

Sequences

Toxin

Protein

• Length: 301 a.a.
• Molecular weight: 32994.82 Da
• Isoelectric Point: 6.4945

>T257457 WP_260675447.1 NZ_CP104279:1829999-1830901 [Comamonas aquatica]
MSANLSASILARLLTLAKQRGDDYSLLLNRFAMERLLARVSTSPYAEHFLLKGALLFALWYDAPHRPTRDADLLGFGPDD
EANLIATFRNIAAMDLGDGIVFDPESVQAQAIREDNTYGGTRITLVARIGSARCALQIDVGFGDAVTPGPQTVAYPTLLD
DFQAPTLRVYPVYTVIAEKYQAMVMLGQANSRMKDFFDLAVIARRTELDGATLAMAIAATFARRQTALPTERPLALTKQF
SEDTAKLRQWQAFLNKNRIGAASLSDTVALLDDLLWPPTRLAAASSQATAIWRPDSLRWV

Nucleotide

• Length: 903 bp

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 22595.15 Da
• Isoelectric Point: 9.6698

>AT257457 WP_260675446.1 NZ_CP104279:1829403-1830002 [Comamonas aquatica]
MNQSDHILELARHRRVLRAADVREHGWSPQLLIRLHQAGKLHRLGRGLYALPDAEVTEHQTLIEVCQRVPKAVLCLLSAL
QWHEIGTQLPHEVWVALPEGTQAPALGYPTLRITRLRGAAYSDGIQTVTEHGAPIRVYSAAKTVTDCFKFRNKIGLDVAL
EALKYAWRSRKVTMDELSHFAKINRVERVMQPYLEAITQ

Nucleotide

• Length: 600 bp