Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/RHH(antitoxin)
Location 1227948..1228498 Replicon chromosome
Accession NZ_CP104202
Organism Chlorobaculum sp. MV4-Y

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag NY406_RS05935 Protein ID WP_260533211.1
Coordinates 1227948..1228235 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag NY406_RS05940 Protein ID WP_260533212.1
Coordinates 1228223..1228498 (-) Length 92 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NY406_RS05915 (NY406_05915) 1223063..1223629 + 567 WP_260533208.1 nitroreductase family protein -
NY406_RS05920 (NY406_05920) 1223805..1224740 + 936 WP_260533209.1 hypothetical protein -
NY406_RS05925 (NY406_05925) 1224844..1226820 + 1977 WP_260533210.1 bifunctional UDP-sugar hydrolase/5'-nucleotidase -
NY406_RS05930 (NY406_05930) 1226888..1227043 + 156 WP_260633755.1 hypothetical protein -
NY406_RS05935 (NY406_05935) 1227948..1228235 - 288 WP_260533211.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NY406_RS05940 (NY406_05940) 1228223..1228498 - 276 WP_260533212.1 ribbon-helix-helix protein, CopG family Antitoxin
NY406_RS05945 (NY406_05945) 1228558..1228914 - 357 WP_260633756.1 HAD family acid phosphatase -
NY406_RS05950 (NY406_05950) 1228930..1229205 - 276 WP_260533213.1 hypothetical protein -
NY406_RS05955 (NY406_05955) 1229517..1229936 - 420 WP_260533214.1 OsmC family protein -
NY406_RS05960 (NY406_05960) 1230288..1231343 + 1056 WP_260533215.1 rod shape-determining protein -
NY406_RS05965 (NY406_05965) 1231446..1233179 - 1734 WP_260533216.1 caspase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-94)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-44)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10785.38 Da        Isoelectric Point: 6.7271

>T257389 WP_260533211.1 NZ_CP104202:c1228235-1227948 [Chlorobaculum sp. MV4-Y]
VPEIKWLPEALVDVERLHAFLHEKSPDAASRAARVILDGAGLLQSIPEIGRPMNDETGRRELVISFGAGAFVLRYIWDKN
DTVVIIRVWHSRENR

Download         Length: 288 bp

Antitoxin


Download         Length: 92 a.a.        Molecular weight: 10921.38 Da        Isoelectric Point: 6.7173

>AT257389 WP_260533212.1 NZ_CP104202:c1228498-1228223 [Chlorobaculum sp. MV4-Y]
MSKTKTKGVKLDDTTHKRLEELARIRDRSPHWLMCRAIETYLDREEKYEEEKREDMDRWERYQLTGIAVTHEKAAEWLEN
LAEGKVTACPR

Download         Length: 276 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References