Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1916646..1916791 Replicon chromosome
Accession NZ_CP104196
Organism Klebsiella pneumoniae strain CHN23026

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1916682..1916784 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1916646..1916791 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N3931_RS09375 (N3931_09375) 1911776..1913836 + 2061 WP_206925937.1 oligopeptidase B -
N3931_RS09380 (N3931_09380) 1913840..1914499 - 660 WP_002911407.1 exodeoxyribonuclease X -
N3931_RS09385 (N3931_09385) 1914578..1914808 - 231 WP_040147502.1 DNA polymerase III subunit theta -
N3931_RS09390 (N3931_09390) 1914921..1915295 + 375 WP_004151448.1 CopC domain-containing protein YobA -
N3931_RS09395 (N3931_09395) 1915299..1916168 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
N3931_RS09400 (N3931_09400) 1916185..1916523 + 339 WP_016529031.1 YebY family protein -
- 1916646..1916791 - 146 - - Antitoxin
- 1916682..1916784 + 103 - - Toxin
N3931_RS09405 (N3931_09405) 1917159..1917302 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
N3931_RS09410 (N3931_09410) 1917407..1918375 - 969 WP_004151446.1 VirK/YbjX family protein -
N3931_RS09415 (N3931_09415) 1918532..1919185 + 654 WP_016529030.1 protein-serine/threonine phosphatase -
N3931_RS09420 (N3931_09420) 1919182..1919373 - 192 WP_002911395.1 YebW family protein -
N3931_RS09425 (N3931_09425) 1919471..1919710 - 240 WP_002911393.1 YebV family protein -
N3931_RS09430 (N3931_09430) 1919826..1921259 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T257376 NZ_CP104196:1916682-1916784 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT257376 NZ_CP104196:c1916791-1916646 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References