Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3411643..3412307 Replicon chromosome
Accession NZ_CP104174
Organism Bradyrhizobium sp. CB1015

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2604_RS15595 Protein ID WP_260375509.1
Coordinates 3411643..3412050 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2604_RS15600 Protein ID WP_260375510.1
Coordinates 3412047..3412307 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2604_RS15570 (N2604_15570) 3406684..3407940 + 1257 WP_260375504.1 hydroxysqualene dehydroxylase HpnE -
N2604_RS15575 (N2604_15575) 3408005..3409957 + 1953 WP_260375505.1 squalene--hopene cyclase -
N2604_RS15580 (N2604_15580) 3409954..3410703 + 750 WP_260375506.1 phosphorylase -
N2604_RS15585 (N2604_15585) 3410868..3411143 + 276 WP_260375507.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
N2604_RS15590 (N2604_15590) 3411130..3411522 + 393 WP_260375508.1 type II toxin-antitoxin system VapC family toxin -
N2604_RS15595 (N2604_15595) 3411643..3412050 - 408 WP_260375509.1 type II toxin-antitoxin system VapC family toxin Toxin
N2604_RS15600 (N2604_15600) 3412047..3412307 - 261 WP_260375510.1 antitoxin Antitoxin
N2604_RS15605 (N2604_15605) 3413267..3414172 + 906 WP_260375511.1 integrase core domain-containing protein -
N2604_RS15610 (N2604_15610) 3414366..3415526 - 1161 WP_197946317.1 adenosyl-hopene transferase HpnH -
N2604_RS15615 (N2604_15615) 3415563..3416489 - 927 WP_260375512.1 4-hydroxy-3-methylbut-2-enyl diphosphate reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-126)

Antitoxin

SpoVT-AbrB domain

(8-43)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15122.24 Da        Isoelectric Point: 4.7783

>T257370 WP_260375509.1 NZ_CP104174:c3412050-3411643 [Bradyrhizobium sp. CB1015]
MTKWLLDTNAVIALVTRRSEPLLRRVESTEPGALAISSIVAHELYFGAYRSQKIEFNLETLRLVFTDLDIVDLDQEDARA
AGEIRAELARRSTPIGPYDLLIAGQAIARGLPLVSNNTAEFQRIAGLRLEDWTRD

Download         Length: 408 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9682.93 Da        Isoelectric Point: 10.4317

>AT257370 WP_260375510.1 NZ_CP104174:c3412307-3412047 [Bradyrhizobium sp. CB1015]
MPHIAKVFKSGNSQAVRLPKDFRFSVEEVEVSREGDAVILRPRRSAAGPWASLRAAIARGFSPDFMADGREQPEEQTRPD
LDRAFR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References