Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 556135..556766 Replicon chromosome
Accession NZ_CP104174
Organism Bradyrhizobium sp. CB1015

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2604_RS02590 Protein ID WP_260373646.1
Coordinates 556362..556766 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2604_RS02585 Protein ID WP_260376415.1
Coordinates 556135..556365 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2604_RS02570 (N2604_02570) 552654..553352 - 699 WP_260373643.1 hypothetical protein -
N2604_RS02575 (N2604_02575) 553533..554597 + 1065 WP_260373644.1 LysM peptidoglycan-binding domain-containing protein -
N2604_RS02580 (N2604_02580) 554768..556057 + 1290 WP_260373645.1 Spy/CpxP family protein refolding chaperone -
N2604_RS02585 (N2604_02585) 556135..556365 + 231 WP_260376415.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N2604_RS02590 (N2604_02590) 556362..556766 + 405 WP_260373646.1 PIN domain-containing protein Toxin
N2604_RS02595 (N2604_02595) 556815..557681 - 867 WP_260373647.1 hypothetical protein -
N2604_RS02600 (N2604_02600) 557900..560347 - 2448 WP_260373648.1 adenylate/guanylate cyclase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-118)

Antitoxin

SpoVT-AbrB domain

(5-32)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14548.56 Da        Isoelectric Point: 5.5712

>T257369 WP_260373646.1 NZ_CP104174:556362-556766 [Bradyrhizobium sp. CB1015]
VSAFFDSNILIYAYSTDARRGPALNALAGGGVISAQVLNEFTNVLRKKQQQDWPVIEAAVQTIRFRFPDIVPLTADTHAA
AIALARDHSVAFYDALIIASAIETGCDTLYSEDLQHRRSIGGLTILNPFLGMTP

Download         Length: 405 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8578.86 Da        Isoelectric Point: 7.0143

>AT257369 WP_260376415.1 NZ_CP104174:556135-556365 [Bradyrhizobium sp. CB1015]
VLVSKWGNSLAVRLPKALVEALKLSPGDELNVVKASKGEIAVEKVDKRAEFLKQVEQFHFPLPEGYKFDRDEANER

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References