Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 746490..746995 Replicon chromosome
Accession NZ_CP104164
Organism Candidatus Bandiella numerosa isolate SAG 25.80_endo

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N3Z17_RS03595 Protein ID WP_282471375.1
Coordinates 746490..746744 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N3Z17_RS03600 Protein ID WP_282471376.1
Coordinates 746741..746995 (-) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N3Z17_RS03570 (N3Z17_03570) 741569..743386 + 1818 WP_282471371.1 aspartate--tRNA ligase -
N3Z17_RS03575 (N3Z17_03575) 743400..743768 + 369 WP_282471372.1 holo-ACP synthase -
N3Z17_RS03580 (N3Z17_03580) 743831..744274 + 444 WP_282471373.1 response regulator -
N3Z17_RS03585 (N3Z17_03585) 744294..744905 - 612 WP_282471374.1 M15 family metallopeptidase -
N3Z17_RS03590 (N3Z17_03590) 745029..746240 + 1212 WP_282472630.1 phage portal protein -
N3Z17_RS03595 (N3Z17_03595) 746490..746744 - 255 WP_282471375.1 Txe/YoeB family addiction module toxin Toxin
N3Z17_RS03600 (N3Z17_03600) 746741..746995 - 255 WP_282471376.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N3Z17_RS03605 (N3Z17_03605) 747176..748030 - 855 WP_282471377.1 outer membrane beta-barrel protein -
N3Z17_RS03610 (N3Z17_03610) 748276..748539 + 264 WP_282471378.1 hypothetical protein -
N3Z17_RS03615 (N3Z17_03615) 748547..748822 + 276 WP_282471379.1 hypothetical protein -
N3Z17_RS03620 (N3Z17_03620) 748895..749338 - 444 WP_282471380.1 EVE domain-containing protein -
N3Z17_RS03625 (N3Z17_03625) 749367..749816 + 450 WP_282471381.1 HK97 family phage prohead protease -
N3Z17_RS03635 (N3Z17_03635) 750140..751318 + 1179 WP_282471382.1 phage major capsid protein -
N3Z17_RS03640 (N3Z17_03640) 751387..751878 + 492 WP_282471383.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(1-84)

Antitoxin

(1-72)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10168.97 Da        Isoelectric Point: 9.4670

>T257357 WP_282471375.1 NZ_CP104164:c746744-746490 [Candidatus Bandiella numerosa]
MNLLFLPDAWDDYLYWQKTDKKVLKRINELIKATIREPFCGIGKPEPLKFALINCWSRRINSEHRLVYKIEGNNLIILQC
RYHY

Download         Length: 255 bp


Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9741.12 Da        Isoelectric Point: 6.9764

>AT257357 WP_282471376.1 NZ_CP104164:c746995-746741 [Candidatus Bandiella numerosa]
MDAITYTKARKNFTQTMNKVCDDHAPLIITRQNQKPIVMMSLEDYNSIEETLYLLKNSKNASRLSKALDDLKQSNFSDKQ
LIEE

Download         Length: 255 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References