Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | rlegTA/AbiEii-AbiEi |
Location | 2102809..2104288 | Replicon | plasmid pCB3060_1 |
Accession | NZ_CP104159 | ||
Organism | Rhizobium tropici strain CB3060 |
Toxin (Protein)
Gene name | rlegT | Uniprot ID | - |
Locus tag | N2601_RS28870 | Protein ID | WP_260304479.1 |
Coordinates | 2102809..2103678 (-) | Length | 290 a.a. |
Antitoxin (Protein)
Gene name | rlegA | Uniprot ID | - |
Locus tag | N2601_RS28875 | Protein ID | WP_260304480.1 |
Coordinates | 2103671..2104288 (-) | Length | 206 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
N2601_RS28850 (N2601_28850) | 2098971..2100260 | - | 1290 | WP_260304473.1 | MFS transporter | - |
N2601_RS28855 (N2601_28855) | 2100401..2100817 | - | 417 | WP_260304475.1 | heme-binding protein | - |
N2601_RS28860 (N2601_28860) | 2100889..2101587 | - | 699 | WP_260304476.1 | type 1 glutamine amidotransferase domain-containing protein | - |
N2601_RS28865 (N2601_28865) | 2101740..2102651 | + | 912 | WP_260304477.1 | LysR family transcriptional regulator | - |
N2601_RS28870 (N2601_28870) | 2102809..2103678 | - | 870 | WP_260304479.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | Toxin |
N2601_RS28875 (N2601_28875) | 2103671..2104288 | - | 618 | WP_260304480.1 | type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein | Antitoxin |
N2601_RS28880 (N2601_28880) | 2104595..2105020 | - | 426 | WP_260304481.1 | hypothetical protein | - |
N2601_RS28885 (N2601_28885) | 2105095..2105592 | - | 498 | WP_260304482.1 | histidine kinase | - |
N2601_RS28890 (N2601_28890) | 2106216..2107295 | - | 1080 | WP_260304483.1 | alkene reductase | - |
N2601_RS28895 (N2601_28895) | 2107326..2108066 | - | 741 | WP_260304484.1 | SDR family oxidoreductase | - |
N2601_RS28900 (N2601_28900) | 2108168..2109136 | + | 969 | WP_260304485.1 | LysR family transcriptional regulator | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | katA / icl | 1..2260376 | 2260376 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 290 a.a. Molecular weight: 32436.09 Da Isoelectric Point: 5.1020
>T257356 WP_260304479.1 NZ_CP104159:c2103678-2102809 [Rhizobium tropici]
MAKEIRNLGASVRARLLQLAKASGQTFDLVLTRFALERLLFRLSQSPHAGRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPEPDPMLETFRDILAQQADDGVTFDAETLRVDRIREGLEYGGLRLRMVASISGARVNLTVDIGFGDALEPGAEMLDYPS
MLDFPAPRLRAYARETVIAEKFQAMVMLGRANSRMKDFYDIWILSRSFDFNDDRLARAITATFERRDTPIPTEVPDALTD
AFAKDEEKQRQWHAFAESVAHEPGNLTDVIAEIATFLMPHAVAAARLGK
MAKEIRNLGASVRARLLQLAKASGQTFDLVLTRFALERLLFRLSQSPHAGRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPEPDPMLETFRDILAQQADDGVTFDAETLRVDRIREGLEYGGLRLRMVASISGARVNLTVDIGFGDALEPGAEMLDYPS
MLDFPAPRLRAYARETVIAEKFQAMVMLGRANSRMKDFYDIWILSRSFDFNDDRLARAITATFERRDTPIPTEVPDALTD
AFAKDEEKQRQWHAFAESVAHEPGNLTDVIAEIATFLMPHAVAAARLGK
Download Length: 870 bp
Antitoxin
Download Length: 206 a.a. Molecular weight: 22315.67 Da Isoelectric Point: 9.9240
>AT257356 WP_260304480.1 NZ_CP104159:c2104288-2103671 [Rhizobium tropici]
MPGSVTQRQIARTVLVERGIARLAELRNAGVTAATMSRMERDGEVMRLSRGLYQLADAELDTNHSLAEAAKRAPKAVICL
VSALAFHGLTDQLPRHVWIAIGRRDWAPKPDGTPIRVARFTENLLNEGIETHTVEGVPVKIFGVAKTIADCFRYRNKIGL
SVAIEGLQEALRQRKATPGEIADQAERGGVGTVIRPYVEALTANG
MPGSVTQRQIARTVLVERGIARLAELRNAGVTAATMSRMERDGEVMRLSRGLYQLADAELDTNHSLAEAAKRAPKAVICL
VSALAFHGLTDQLPRHVWIAIGRRDWAPKPDGTPIRVARFTENLLNEGIETHTVEGVPVKIFGVAKTIADCFRYRNKIGL
SVAIEGLQEALRQRKATPGEIADQAERGGVGTVIRPYVEALTANG
Download Length: 618 bp
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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