Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 699959..700641 Replicon plasmid pCB3060_1
Accession NZ_CP104159
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2601_RS22655 Protein ID WP_104826581.1
Coordinates 699959..700381 (-) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2601_RS22660 Protein ID WP_104826582.1
Coordinates 700378..700641 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS22645 (N2601_22645) 695227..697713 + 2487 WP_260304997.1 malto-oligosyltrehalose synthase -
N2601_RS22650 (N2601_22650) 697803..699878 + 2076 WP_260304998.1 glycogen debranching protein GlgX -
N2601_RS22655 (N2601_22655) 699959..700381 - 423 WP_104826581.1 type II toxin-antitoxin system VapC family toxin Toxin
N2601_RS22660 (N2601_22660) 700378..700641 - 264 WP_104826582.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N2601_RS22665 (N2601_22665) 700754..701755 - 1002 WP_260304999.1 YihY/virulence factor BrkB family protein -
N2601_RS22670 (N2601_22670) 701965..704238 - 2274 WP_260305000.1 cation:proton antiporter -
N2601_RS22675 (N2601_22675) 704838..705554 + 717 WP_104826585.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - katA / icl 1..2260376 2260376


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-58)


Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 15592.90 Da        Isoelectric Point: 5.2291

>T257355 WP_104826581.1 NZ_CP104159:c700381-699959 [Rhizobium tropici]
VRLLLDTNVLSEVTRPRPDAHVLKWLDGLDEDRSFISVVSIAEIRRGVALMDSGRKRDALTEWLAQDLPQRFEHRVLPVN
EPVAVAWGDLMGLAKRNGRGLSSMDGLIAATAIAHDLTLATRNIRDFEGFGIELVDPWVV

Download         Length: 423 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9630.90 Da        Isoelectric Point: 8.0256

>AT257355 WP_104826582.1 NZ_CP104159:c700641-700378 [Rhizobium tropici]
MRPTPSEQNWTVASAKAKLSEVIECAQSAPQTITRNGKPSVVVVSAEEWHRKTARKGTLAEFLMGSPLRGADLDLERQRD
DPRDLSL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References