257354

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 4053504..4054147 Replicon chromosome
Accession NZ_CP104158
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2601_RS19540 Protein ID WP_104821786.1
Coordinates 4053504..4053908 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2601_RS19545 Protein ID WP_104821787.1
Coordinates 4053905..4054147 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS19505 (N2601_19505) 4048601..4049506 + 906 WP_104821779.1 LysR family transcriptional regulator -
N2601_RS19510 (N2601_19510) 4049507..4050382 - 876 WP_104821780.1 LysR family transcriptional regulator -
N2601_RS19515 (N2601_19515) 4050479..4051762 + 1284 WP_104821781.1 MFS transporter -
N2601_RS19520 (N2601_19520) 4051785..4052171 + 387 WP_104821782.1 VOC family protein -
N2601_RS19525 (N2601_19525) 4052290..4052631 + 342 WP_104821783.1 metalloregulator ArsR/SmtB family transcription factor -
N2601_RS19530 (N2601_19530) 4052615..4053097 + 483 WP_104821784.1 SRPBCC domain-containing protein -
N2601_RS19535 (N2601_19535) 4053103..4053507 + 405 WP_104821785.1 GFA family protein -
N2601_RS19540 (N2601_19540) 4053504..4053908 - 405 WP_104821786.1 type II toxin-antitoxin system VapC family toxin Toxin
N2601_RS19545 (N2601_19545) 4053905..4054147 - 243 WP_104821787.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N2601_RS19550 (N2601_19550) 4054213..4054887 - 675 WP_104821788.1 hypothetical protein -
N2601_RS19555 (N2601_19555) 4055013..4056674 - 1662 WP_104821789.1 urocanate hydratase -
N2601_RS19560 (N2601_19560) 4056717..4057046 - 330 WP_104821790.1 TfoX/Sxy family protein -
N2601_RS19565 (N2601_19565) 4057065..4058165 - 1101 WP_104821791.1 DUF917 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

SpoVT-AbrB domain

(7-44)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15055.16 Da        Isoelectric Point: 6.4885

>T257354 WP_104821786.1 NZ_CP104158:c4053908-4053504 [Rhizobium tropici]
VKYLLDSNAVIALMKGHTGFVSELRRHKPQDFAISAIVAHELFYGAYKGQRVADNLVRVDALQFETLDFDREDARVAGEI
RANLASLGTPIGAYDVLIAGQAVARDLILITRNVREFERVHKLRFEDWESLPSS

Download         Length: 405 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9337.45 Da        Isoelectric Point: 4.3430

>AT257354 WP_104821787.1 NZ_CP104158:c4054147-4053905 [Rhizobium tropici]
MDTAKIFWSGRSQAIRLPKEFRLDGEEVRIRRQGKAIILEPIAEDWDWLESVTGPVDHDFEEAATEQPAEQQRPELDIFK

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References