Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) vapBC/Phd-VapC
Location 2464058..2464722 Replicon chromosome
Accession NZ_CP104158
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2601_RS12010 Protein ID WP_260303101.1
Coordinates 2464058..2464312 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2601_RS12015 Protein ID WP_260303102.1
Coordinates 2464312..2464722 (+) Length 137 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS11980 (N2601_11980) 2459570..2460151 + 582 WP_104824045.1 NAD(P)H-dependent oxidoreductase -
N2601_RS11985 (N2601_11985) 2460195..2460584 - 390 WP_104825181.1 Rid family hydrolase -
N2601_RS11990 (N2601_11990) 2460697..2461593 - 897 WP_104824046.1 DMT family transporter -
N2601_RS11995 (N2601_11995) 2461793..2462230 + 438 WP_260303098.1 hypothetical protein -
N2601_RS12000 (N2601_12000) 2462262..2462879 - 618 WP_260303099.1 alpha/beta hydrolase -
N2601_RS12005 (N2601_12005) 2462893..2463825 - 933 WP_260303100.1 VOC family protein -
N2601_RS12010 (N2601_12010) 2464058..2464312 + 255 WP_260303101.1 type II toxin-antitoxin system Phd/YefM family antitoxin Toxin
N2601_RS12015 (N2601_12015) 2464312..2464722 + 411 WP_260303102.1 type II toxin-antitoxin system VapC family toxin Antitoxin
N2601_RS12020 (N2601_12020) 2464716..2465417 - 702 WP_260303103.1 uracil-DNA glycosylase -
N2601_RS12025 (N2601_12025) 2465507..2466121 - 615 WP_260303104.1 septation protein IspZ -
N2601_RS12030 (N2601_12030) 2466236..2468683 - 2448 WP_260303105.1 FAD-dependent oxidoreductase -
N2601_RS12035 (N2601_12035) 2468693..2469571 - 879 WP_104824055.1 choline kinase family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(3-63)

Antitoxin

(2-116)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 9200.27 Da        Isoelectric Point: 4.4165

>T257350 WP_260303101.1 NZ_CP104158:2464058-2464312 [Rhizobium tropici]
MDWPLQDAKNQFSKVVQKARSEGPQTVTLRGERAAVVLSAEDYDALRAGKPSLVDDLLSGPAWDDELADAVITRDKTPSR
DVAF

Download         Length: 255 bp


Antitoxin


Download         Length: 137 a.a.        Molecular weight: 15182.37 Da        Isoelectric Point: 6.4860

>AT257350 WP_260303102.1 NZ_CP104158:2464312-2464722 [Rhizobium tropici]
MYLIDTNIISEARRGTIEAISWLRIADPSTVYLSVITLGEVMRGIALKRRTDPRAAAHLEEWLRKLRHDHSGRILPITDQ
IAVEWGRISALRPRGDADGLIAATAIVHDLIIVTRNVSDFDDAGVSVINPWDQASY

Download         Length: 411 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References