Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 721167..721726 Replicon chromosome
Accession NZ_CP104158
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2601_RS03560 Protein ID WP_104822466.1
Coordinates 721167..721532 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2601_RS03565 Protein ID WP_104822467.1
Coordinates 721529..721726 (-) Length 66 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS03540 (N2601_03540) 716203..717447 - 1245 WP_104822464.1 efflux RND transporter periplasmic adaptor subunit -
N2601_RS03545 (N2601_03545) 717879..718668 - 790 Protein_702 SDR family oxidoreductase -
N2601_RS03550 (N2601_03550) 718954..720618 + 1665 WP_104822465.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
N2601_RS03555 (N2601_03555) 720624..721151 + 528 WP_104825033.1 GNAT family N-acetyltransferase -
N2601_RS03560 (N2601_03560) 721167..721532 - 366 WP_104822466.1 PIN domain-containing protein Toxin
N2601_RS03565 (N2601_03565) 721529..721726 - 198 WP_104822467.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N2601_RS03570 (N2601_03570) 721829..722731 - 903 WP_104822468.1 DMT family transporter -
N2601_RS03575 (N2601_03575) 722877..723350 + 474 WP_104822469.1 Lrp/AsnC family transcriptional regulator -
N2601_RS03580 (N2601_03580) 723401..724774 - 1374 WP_104822470.1 magnesium transporter -
N2601_RS03585 (N2601_03585) 724973..725161 - 189 WP_158704428.1 hypothetical protein -
N2601_RS03590 (N2601_03590) 725172..726380 - 1209 WP_245463969.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-47)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13818.11 Da        Isoelectric Point: 8.4792

>T257348 WP_104822466.1 NZ_CP104158:c721532-721167 [Rhizobium tropici]
MILVDTSIWIDHFHSLDAKLQSLLEQKQVLIHPFVIGEISLGNLRQYDLVMRSLSRLYQISKAPDDDVLYFIRSNRLQGM
GIGYVDAHLAAAAILTPGTYLWTRDKRLQRVAENLRIAALL

Download         Length: 366 bp

Antitoxin


Download         Length: 66 a.a.        Molecular weight: 7174.25 Da        Isoelectric Point: 5.0959

>AT257348 WP_104822467.1 NZ_CP104158:c721726-721529 [Rhizobium tropici]
MRTTVTIDDKLLADAREVTELAETSAIVREALKALIEREAARTLIRLGGTEPDIAAPPRRRFGVE

Download         Length: 198 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References