257347

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 587957..588534 Replicon chromosome
Accession NZ_CP104158
Organism Rhizobium tropici strain CB3060

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag N2601_RS02900 Protein ID WP_104822357.1
Coordinates 588244..588534 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag N2601_RS02895 Protein ID WP_104822356.1
Coordinates 587957..588241 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2601_RS02880 (N2601_02880) 584815..585813 + 999 WP_104822353.1 NAD(P)H-quinone oxidoreductase -
N2601_RS02885 (N2601_02885) 585794..587221 - 1428 WP_104822354.1 MFS transporter -
N2601_RS02890 (N2601_02890) 587323..587946 + 624 WP_104822355.1 MarR family transcriptional regulator -
N2601_RS02895 (N2601_02895) 587957..588241 - 285 WP_104822356.1 putative addiction module antidote protein Antitoxin
N2601_RS02900 (N2601_02900) 588244..588534 - 291 WP_104822357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2601_RS02905 (N2601_02905) 588714..589721 + 1008 WP_104822358.1 asparaginase -
N2601_RS02910 (N2601_02910) 589768..590529 - 762 WP_104825017.1 DeoR/GlpR family DNA-binding transcription regulator -
N2601_RS02915 (N2601_02915) 590652..591008 + 357 WP_104822359.1 DUF4406 domain-containing protein -
N2601_RS02920 (N2601_02920) 591148..591768 + 621 WP_104822360.1 glutathione S-transferase N-terminal domain-containing protein -
N2601_RS02925 (N2601_02925) 591769..592125 - 357 WP_104825018.1 MmcQ/YjbR family DNA-binding protein -
N2601_RS02930 (N2601_02930) 592244..592429 - 186 WP_104822361.1 hypothetical protein -
N2601_RS02935 (N2601_02935) 592577..593473 + 897 WP_104822362.1 LysR substrate-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(46-90)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10666.35 Da        Isoelectric Point: 9.7931

>T257347 WP_104822357.1 NZ_CP104158:c588534-588244 [Rhizobium tropici]
MIEIRQTAEFAEWLGKIKDINAVARIQVRIRRLSLGNPGDVKPVGEGISELRIDYGPGYRLYYHKRGQELVLLLCGGDKS
TQNADIAKAKALAKEA

Download         Length: 291 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 9883.22 Da        Isoelectric Point: 4.4488

>AT257347 WP_104822356.1 NZ_CP104158:c588241-587957 [Rhizobium tropici]
MALETKPWDPTEHLDSPEAIAAYVEAAFEDGDPALIAAVIGDVARARGMTQLAKEAGVSRETIYKAFSEGGNPTLETLSG
VIRALGLKLTVRAA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References