Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2284630..2285273 Replicon plasmid pWSM1592_1
Accession NZ_CP104144
Organism Rhizobium sullae strain WSM1592

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2599_RS31765 Protein ID WP_027509125.1
Coordinates 2284887..2285273 (+) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N0DGB0
Locus tag N2599_RS31760 Protein ID WP_027509126.1
Coordinates 2284630..2284887 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2599_RS31740 (N2599_31740) 2280303..2281184 - 882 WP_027509131.1 carbohydrate ABC transporter permease -
N2599_RS31745 (N2599_31745) 2281195..2282124 - 930 WP_027509130.1 sugar ABC transporter permease -
N2599_RS31750 (N2599_31750) 2282121..2283236 - 1116 WP_027509129.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
N2599_RS31755 (N2599_31755) 2283267..2283977 - 711 WP_037141473.1 GntR family transcriptional regulator -
N2599_RS31760 (N2599_31760) 2284630..2284887 + 258 WP_027509126.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N2599_RS31765 (N2599_31765) 2284887..2285273 + 387 WP_027509125.1 type II toxin-antitoxin system VapC family toxin Toxin
N2599_RS31770 (N2599_31770) 2285270..2285535 + 266 Protein_2241 integrase -
N2599_RS31775 (N2599_31775) 2285553..2285819 + 267 WP_260308594.1 DUF2218 domain-containing protein -
N2599_RS31780 (N2599_31780) 2286099..2287775 - 1677 WP_027509123.1 iron ABC transporter permease -
N2599_RS31785 (N2599_31785) 2287819..2288814 - 996 WP_245209221.1 Fe(3+) ABC transporter substrate-binding protein -
N2599_RS31790 (N2599_31790) 2288933..2290024 - 1092 WP_084606421.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..2759627 2759627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-84)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13925.10 Da        Isoelectric Point: 4.5849

>T257341 WP_027509125.1 NZ_CP104144:2284887-2285273 [Rhizobium sullae]
MVIDTSAIVAVLRSEPEAAALERKVVANPIRLVPATCVLEARMVLVSRRGEHALAEIDLWLARIEADIVPVDADLVDLAT
QAWLAYGKGRHPAGLNFPDCFSYALAKRADEPLLFIGKDFSQTDIEAA

Download         Length: 387 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9463.78 Da        Isoelectric Point: 6.7254

>AT257341 WP_027509126.1 NZ_CP104144:2284630-2284887 [Rhizobium sullae]
MSLNIKNPATVALVDELARRQGISKTAAIHQALTERLHRMGYGGVAQERLLTEMQAIRGRLARLPELDSRSDEEIIGYDE
HGIPN

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N0DGB0

References