Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-VagC
Location 2127670..2128343 Replicon plasmid pWSM1592_1
Accession NZ_CP104144
Organism Rhizobium sullae strain WSM1592

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2599_RS30930 Protein ID WP_027512588.1
Coordinates 2127939..2128343 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID A0A2N0D874
Locus tag N2599_RS30925 Protein ID WP_027512589.1
Coordinates 2127670..2127942 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2599_RS30885 (N2599_30885) 2122790..2124384 - 1595 Protein_2064 gamma-glutamyltransferase -
N2599_RS30890 (N2599_30890) 2124420..2124716 - 297 Protein_2065 ABC transporter permease subunit -
N2599_RS30895 (N2599_30895) 2124905..2125246 + 342 WP_244564664.1 hypothetical protein -
N2599_RS30900 (N2599_30900) 2125618..2126049 + 432 WP_027512593.1 YeeE/YedE thiosulfate transporter family protein -
N2599_RS30905 (N2599_30905) 2126046..2126486 + 441 WP_027512592.1 transporter -
N2599_RS30910 (N2599_30910) 2126498..2126647 + 150 Protein_2069 integrase -
N2599_RS30915 (N2599_30915) 2126670..2126996 - 327 WP_027512591.1 helix-turn-helix transcriptional regulator -
N2599_RS30920 (N2599_30920) 2126989..2127354 - 366 WP_027512590.1 type II toxin-antitoxin system RelE/ParE family toxin -
N2599_RS30925 (N2599_30925) 2127670..2127942 + 273 WP_027512589.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
N2599_RS30930 (N2599_30930) 2127939..2128343 + 405 WP_027512588.1 type II toxin-antitoxin system VapC family toxin Toxin
N2599_RS30935 (N2599_30935) 2128544..2128989 + 446 Protein_2074 recombinase family protein -
N2599_RS30940 (N2599_30940) 2129018..2131135 - 2118 WP_027512586.1 carboxy terminal-processing peptidase -
N2599_RS30945 (N2599_30945) 2131553..2132347 + 795 WP_027512584.1 exodeoxyribonuclease III -
N2599_RS30950 (N2599_30950) 2132701..2133047 + 347 Protein_2077 type II toxin-antitoxin system RelE/ParE family toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..2759627 2759627


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(16-53)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14715.22 Da        Isoelectric Point: 5.2351

>T257340 WP_027512588.1 NZ_CP104144:2127939-2128343 [Rhizobium sullae]
MNGYLLDTKIISDIIRNPFGPAARRIEEIDPKEICTSIIVAAELRYGCAKKGSAKLLAKVESVLETLPILPMDIPADIKY
GAIRAELEAAGQTLGLNDLLIAAHACALDLTLVTDNTREFQRIRGLTLENWIVR

Download         Length: 405 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10248.77 Da        Isoelectric Point: 4.6909

>AT257340 WP_027512589.1 NZ_CP104144:2127670-2127942 [Rhizobium sullae]
MPISLPSSRPKEVKLFRNNRSQAVRIPAEFELPGDRVMIHREGDKLIIEPVTGPSNFAELIAEWKKEPPLGPEDQFPDIE
DMPAKPENIF

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N0D874

References