Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 851638..852428 Replicon plasmid pWSM1274_1
Accession NZ_CP104139
Organism Rhizobium leguminosarum bv. viciae strain WSM1274

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag N2600_RS28250 Protein ID WP_222351353.1
Coordinates 851931..852428 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag N2600_RS28245 Protein ID WP_222282267.1
Coordinates 851638..851934 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2600_RS28210 (N2600_28210) 847371..847577 + 207 Protein_795 hypothetical protein -
N2600_RS28215 (N2600_28215) 847607..848371 - 765 WP_260299015.1 Crp/Fnr family transcriptional regulator -
N2600_RS28220 (N2600_28220) 848476..848711 - 236 Protein_797 hypothetical protein -
N2600_RS28225 (N2600_28225) 849307..849483 + 177 Protein_798 DUF1515 domain-containing protein -
N2600_RS28230 (N2600_28230) 849958..850446 + 489 WP_170283121.1 hypothetical protein -
N2600_RS28235 (N2600_28235) 850590..850784 + 195 WP_260299495.1 hypothetical protein -
N2600_RS28240 (N2600_28240) 850940..851310 - 371 Protein_801 transposase -
N2600_RS28245 (N2600_28245) 851638..851934 + 297 WP_222282267.1 DUF1778 domain-containing protein Antitoxin
N2600_RS28250 (N2600_28250) 851931..852428 + 498 WP_222351353.1 GNAT family N-acetyltransferase Toxin
N2600_RS28255 (N2600_28255) 852762..854930 + 2169 WP_260299016.1 EAL domain-containing protein -
N2600_RS28260 (N2600_28260) 855743..855970 - 228 WP_260299017.1 hypothetical protein -
N2600_RS28265 (N2600_28265) 856285..856502 + 218 Protein_806 helix-turn-helix domain-containing protein -
N2600_RS28270 (N2600_28270) 856872..857143 - 272 Protein_807 PAS domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1180112 1180112
- flank IS/Tn - - 851008..851310 302


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(67-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17782.34 Da        Isoelectric Point: 7.4217

>T257330 WP_222351353.1 NZ_CP104139:851931-852428 [Rhizobium leguminosarum bv. viciae]
VTLSVPAPLADHHELAEFHSGVPELDDWLRLRARANQASGASRTFVVCEASRVIAYYALASGAVRQSEAPGRFRRNMPDP
IPVAVLGRLAIDQTYQGRGFGRALVRDAGLRLINAAEILGIRGVLVHAISDDARAFYQAVGFLPSPSDPMMLLVGLHDLN
NALTS

Download         Length: 498 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11147.74 Da        Isoelectric Point: 8.5685

>AT257330 WP_222282267.1 NZ_CP104139:851638-851934 [Rhizobium leguminosarum bv. viciae]
MPTSHPSKRPDASVALNMRIKPATRNLIDRAAEMLGKTRTDFMLEASERRAEEVLLDRTIFTVSAEVYAEYLARLDAPTQ
PNERLKRTMSTKAPWDEA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References