Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 840874..841544 Replicon plasmid pWSM1274_1
Accession NZ_CP104139
Organism Rhizobium leguminosarum bv. viciae strain WSM1274

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N2600_RS28185 Protein ID WP_260299012.1
Coordinates 841125..841544 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N2600_RS28180 Protein ID WP_170283097.1
Coordinates 840874..841128 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2600_RS28150 (N2600_28150) 836141..836518 - 378 Protein_783 transposase -
N2600_RS28155 (N2600_28155) 836732..837610 + 879 WP_260299008.1 SDR family oxidoreductase -
N2600_RS28160 (N2600_28160) 837790..838248 - 459 WP_260299009.1 DUF305 domain-containing protein -
N2600_RS28165 (N2600_28165) 838538..838957 - 420 WP_260299010.1 GNAT family N-acetyltransferase -
N2600_RS28170 (N2600_28170) 839451..840374 - 924 WP_260299011.1 LuxR C-terminal-related transcriptional regulator -
N2600_RS28175 (N2600_28175) 840371..840598 - 228 WP_206120837.1 CopG family transcriptional regulator -
N2600_RS28180 (N2600_28180) 840874..841128 + 255 WP_170283097.1 plasmid stabilization protein Antitoxin
N2600_RS28185 (N2600_28185) 841125..841544 + 420 WP_260299012.1 type II toxin-antitoxin system VapC family toxin Toxin
N2600_RS28190 (N2600_28190) 841972..842100 - 129 Protein_791 IS256 family transposase -
N2600_RS28195 (N2600_28195) 842472..843620 + 1149 WP_260299013.1 hypothetical protein -
N2600_RS28200 (N2600_28200) 843921..845177 - 1257 WP_170283095.1 sodium:proton antiporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1180112 1180112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 15097.35 Da        Isoelectric Point: 5.1864

>T257329 WP_260299012.1 NZ_CP104139:841125-841544 [Rhizobium leguminosarum bv. viciae]
MILLDTNVISEPWKPVPDEAVIAWLDAQAIETLFLSAITIAELRSGIAAMPSGKRQTILRDRLEGEVLPHFSERILSFDL
AASQFYSELMARARVSGRAIGTADGYIAATAAANGLAIATRDTSPFEAARLKVINPWSR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9243.45 Da        Isoelectric Point: 6.7273

>AT257329 WP_170283097.1 NZ_CP104139:840874-841128 [Rhizobium leguminosarum bv. viciae]
MPAVTIRNLSDETHRALRVRAAHHGRSTEAEIRDIIEAAVRPPERIKLGSLLTAIGRDAGLSDSDVEAIQKSRDKTPAEP
MTFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References