Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 719618..720216 Replicon plasmid pWSM1274_1
Accession NZ_CP104139
Organism Rhizobium leguminosarum bv. viciae strain WSM1274

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag N2600_RS27525 Protein ID WP_130728017.1
Coordinates 719923..720216 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A7Y2RA27
Locus tag N2600_RS27520 Protein ID WP_018068225.1
Coordinates 719618..719926 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2600_RS27500 (N2600_27500) 716421..716579 + 159 WP_003549679.1 cbb3-type cytochrome oxidase assembly protein CcoS -
N2600_RS27505 (N2600_27505) 716614..717285 + 672 WP_011654245.1 Crp/Fnr family transcriptional regulator -
N2600_RS27510 (N2600_27510) 717644..718357 - 714 WP_003549684.1 GntR family transcriptional regulator -
N2600_RS27515 (N2600_27515) 718975..719343 - 369 Protein_656 transposase -
N2600_RS27520 (N2600_27520) 719618..719926 + 309 WP_018068225.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
N2600_RS27525 (N2600_27525) 719923..720216 + 294 WP_130728017.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N2600_RS27530 (N2600_27530) 720545..721861 - 1317 WP_260299460.1 aspartate--tRNA(Asn) ligase -
N2600_RS27535 (N2600_27535) 722293..722916 + 624 WP_260298954.1 recombinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1180112 1180112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-89)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-58)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 10692.31 Da        Isoelectric Point: 8.5412

>T257328 WP_130728017.1 NZ_CP104139:719923-720216 [Rhizobium leguminosarum bv. viciae]
VKLTWSAFALSDRDAIFTYIEAENPSAAILVDERIVAAVRRLVDFPASGRVGRIAGTRELVINGTPYVAAYAITETAVRI
LRILHGAQEWPDTLPKR

Download         Length: 294 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11010.38 Da        Isoelectric Point: 5.1570

>AT257328 WP_018068225.1 NZ_CP104139:719618-719926 [Rhizobium leguminosarum bv. viciae]
MAANALVQTRIDAEVRDRASAVLGNMGLTVSDAVRILLTRTANEGALPLELLSGSEAHDAWFRTKVLEALNDIRPDVSDD
EVEAHFAERRAAARLNAGARKS

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A7Y2RA27

References