Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 180911..181713 Replicon plasmid pWSM1274_1
Accession NZ_CP104139
Organism Rhizobium leguminosarum bv. viciae strain WSM1274

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag N2600_RS25090 Protein ID WP_260299219.1
Coordinates 180911..181438 (-) Length 176 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag N2600_RS25095 Protein ID WP_260299220.1
Coordinates 181435..181713 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N2600_RS25070 (N2600_25070) 176410..177354 + 945 WP_260299216.1 type II secretion system F family protein -
N2600_RS25075 (N2600_25075) 177370..178674 + 1305 WP_260299217.1 AAA family ATPase -
N2600_RS25080 (N2600_25080) 178739..179299 + 561 WP_260299218.1 hypothetical protein -
N2600_RS25085 (N2600_25085) 179512..180033 - 522 WP_026154513.1 tetratricopeptide repeat protein -
N2600_RS25090 (N2600_25090) 180911..181438 - 528 WP_260299219.1 GNAT family N-acetyltransferase Toxin
N2600_RS25095 (N2600_25095) 181435..181713 - 279 WP_260299220.1 DUF1778 domain-containing protein Antitoxin
N2600_RS25100 (N2600_25100) 181918..182748 - 831 WP_260299481.1 DUF6030 family protein -
N2600_RS25105 (N2600_25105) 183197..185311 - 2115 WP_260299221.1 carboxy terminal-processing peptidase -
N2600_RS25110 (N2600_25110) 185461..185940 - 480 WP_260299222.1 MEKHLA domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Conjugative plasmid - - 1..1180112 1180112


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(12-87)


Sequences

Toxin        


Download         Length: 176 a.a.        Molecular weight: 18688.68 Da        Isoelectric Point: 8.8575

>T257326 WP_260299219.1 NZ_CP104139:c181438-180911 [Rhizobium leguminosarum bv. viciae]
VTLPVWHEEPIAKSHDRAAFDCGDAAMNEFIRRFARQSHEQNAAKTFCAIDKAQPDCILGFYTVAPSAVTHEAVPPKITR
GLARHEVAGFKLARLATDIKVAGKGLGGQLIAAAALRCLRLASEGGGILLIIDAKSERAAHWYAGYGAEPLQGKPLTLVM
PLATFAADFKAKGLL

Download         Length: 528 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10114.79 Da        Isoelectric Point: 8.6184

>AT257326 WP_260299220.1 NZ_CP104139:c181713-181435 [Rhizobium leguminosarum bv. viciae]
MPRTADSKTERYQLRIPPKQKALIARAAALSNKDMADFILDKIVPEAEAVIQAAEVEAVSSRDFIRILDLLEHPPKPNAK
LRAAISALPDAL

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References