Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 616252..616922 Replicon plasmid pC101c
Accession NZ_CP104137
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0R80_RS30520 Protein ID WP_275598668.1
Coordinates 616252..616671 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0R80_RS30525 Protein ID WP_275598667.1
Coordinates 616668..616922 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0R80_RS30500 (N0R80_30505) 611358..612274 - 917 Protein_604 DnaJ C-terminal domain-containing protein -
N0R80_RS30505 (N0R80_30510) 612357..612719 - 363 WP_275598670.1 response regulator -
N0R80_RS30510 (N0R80_30515) 612746..615280 - 2535 WP_275598689.1 PAS domain S-box protein -
N0R80_RS30515 (N0R80_30520) 615676..616083 + 408 WP_275598669.1 GFA family protein -
N0R80_RS30520 (N0R80_30525) 616252..616671 - 420 WP_275598668.1 type II toxin-antitoxin system VapC family toxin Toxin
N0R80_RS30525 (N0R80_30530) 616668..616922 - 255 WP_275598667.1 plasmid stabilization protein Antitoxin
N0R80_RS30530 (N0R80_30535) 617111..618073 - 963 WP_275598666.1 ATP-binding cassette domain-containing protein -
N0R80_RS30535 (N0R80_30540) 618070..618982 - 913 Protein_611 ABC transporter ATP-binding protein -
N0R80_RS30540 (N0R80_30545) 618979..619800 - 822 WP_275598664.1 ABC transporter permease -
N0R80_RS30545 (N0R80_30550) 619806..620741 - 936 WP_275598663.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..772646 772646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14859.15 Da        Isoelectric Point: 5.7116

>T257323 WP_275598668.1 NZ_CP104137:c616671-616252 [Sinorhizobium sp. C101]
MIVLDTNVVSEVMKPAADPAVRSWLNEQVAETLYLASVTLAELLFGIGALPDGRRKKALAEMFDGVLELFGDRVLPFDIG
AARYYAGLAVTARAAGKGFPTPDGYIAAIAASRGFLVATRDISPFEAAGLTVVNPWHHR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9526.90 Da        Isoelectric Point: 6.4732

>AT257323 WP_275598667.1 NZ_CP104137:c616922-616668 [Sinorhizobium sp. C101]
MAILTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRVRMGDALAELGRRLGLTNDDFAVFDEIRDKAPAQP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References