257321

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-Xre
Location 713667..714599 Replicon plasmid pC101b
Accession NZ_CP104136
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag N0R80_RS22850 Protein ID WP_275598965.1
Coordinates 713667..714221 (-) Length 185 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A2N8JW20
Locus tag N0R80_RS22855 Protein ID WP_018097157.1
Coordinates 714228..714599 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0R80_RS22835 (N0R80_22835) 709128..710231 + 1104 WP_275598968.1 sulfate/molybdate ABC transporter ATP-binding protein -
N0R80_RS22840 (N0R80_22840) 710343..711707 + 1365 WP_275598967.1 FAD-binding oxidoreductase -
N0R80_RS22845 (N0R80_22845) 712017..712958 - 942 WP_275600181.1 IS110 family transposase -
N0R80_RS22850 (N0R80_22850) 713667..714221 - 555 WP_275598965.1 RES family NAD+ phosphorylase Toxin
N0R80_RS22855 (N0R80_22855) 714228..714599 - 372 WP_018097157.1 DUF2384 domain-containing protein Antitoxin
N0R80_RS22860 (N0R80_22860) 714676..715461 - 786 WP_275598964.1 crotonase/enoyl-CoA hydratase family protein -
N0R80_RS22865 (N0R80_22865) 715458..716327 - 870 WP_275600182.1 hydroxymethylglutaryl-CoA lyase -
N0R80_RS22870 (N0R80_22870) 716324..718311 - 1988 Protein_659 acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha -
N0R80_RS22875 (N0R80_22875) 718329..718712 - 384 WP_100670781.1 RidA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695765 1695765


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(23-177)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-120)


Sequences

Toxin        


Download         Length: 185 a.a.        Molecular weight: 20341.28 Da        Isoelectric Point: 6.7527

>T257321 WP_275598965.1 NZ_CP104136:c714221-713667 [Sinorhizobium sp. C101]
MRKHSPLVSRPDPEPTASVEPITLWRAFVPRWAHMPLSGAGAARFGGRWNPIGVPAIYGARELSTAWAEYNQGFVQHPAL
IVQLELLGARLADLTDVSLLVELGVDEAIHRCEWRDALDKGAVPETHRLQSELLARDFHGVIYPSFMSPGGTCVALWRWN
GPQEPRLGVIDPDGRLPKSPASWV

Download         Length: 555 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13109.26 Da        Isoelectric Point: 9.9996

>AT257321 WP_018097157.1 NZ_CP104136:c714599-714228 [Sinorhizobium sp. C101]
MIALDFQIPAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLESVRAGVYA

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8JW20

References