Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 563078..563885 Replicon plasmid pC101b
Accession NZ_CP104136
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag N0R80_RS22195 Protein ID WP_100670374.1
Coordinates 563361..563885 (+) Length 175 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A2N8JWE8
Locus tag N0R80_RS22190 Protein ID WP_018097027.1
Coordinates 563078..563368 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0R80_RS22165 (N0R80_22165) 558078..559028 - 951 WP_275599053.1 succinoglycan biosynthesis protein ExoV -
N0R80_RS22170 (N0R80_22170) 559143..560100 - 958 Protein_519 succinoglycan biosynthesis glycosyltransferase ExoW -
N0R80_RS22175 (N0R80_22175) 560224..561708 + 1485 WP_275599052.1 succinoglycan biosynthesis transport protein ExoT -
N0R80_RS22180 (N0R80_22180) 562084..562658 + 575 Protein_521 thermonuclease family protein -
N0R80_RS22185 (N0R80_22185) 562678..562935 + 258 WP_018097026.1 hypothetical protein -
N0R80_RS22190 (N0R80_22190) 563078..563368 + 291 WP_018097027.1 DUF1778 domain-containing protein Antitoxin
N0R80_RS22195 (N0R80_22195) 563361..563885 + 525 WP_100670374.1 GNAT family N-acetyltransferase Toxin
N0R80_RS22200 (N0R80_22200) 564417..564800 - 384 WP_102762399.1 VOC family protein -
N0R80_RS22205 (N0R80_22205) 564948..565448 - 501 WP_275599050.1 GNAT family N-acetyltransferase -
N0R80_RS22210 (N0R80_22210) 565451..566581 - 1131 WP_275599049.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
N0R80_RS22215 (N0R80_22215) 566670..567899 - 1230 WP_275599048.1 extracellular solute-binding protein -
N0R80_RS22220 (N0R80_22220) 567928..568785 - 858 WP_100670384.1 carbohydrate ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695765 1695765


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 18532.30 Da        Isoelectric Point: 7.3207

>T257320 WP_100670374.1 NZ_CP104136:563361-563885 [Sinorhizobium sp. C101]
VLDWREEPIGRHHDRKAFDCGTPELNEYLRRHARQNHEGGGSKTFVAVAPTAPETILGYYSISPASIAFAKVPAPLTKGL
GRYEVAVYRLARLAVALPLQGRGLGGDLLLAAGARALAVAAQVGGVALAIDAKDEKAACWYERFGAMPLLDSSPLSLILP
FKTIIDALDAAQGE

Download         Length: 525 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10730.29 Da        Isoelectric Point: 10.6264

>AT257320 WP_018097027.1 NZ_CP104136:563078-563368 [Sinorhizobium sp. C101]
MAQMQANRDDRIELRTTRDEKRLLTAAAAHERLDVTSFIMRAVLPAAREVVENAERISLSERDSLRVLDLLENPPAPTPA
LLAAARRRIARDGKSA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8JWE8

References