Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 464820..465490 Replicon plasmid pC101b
Accession NZ_CP104136
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0R80_RS21730 Protein ID WP_275599104.1
Coordinates 465044..465490 (+) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0R80_RS21725 Protein ID WP_080636789.1
Coordinates 464820..465047 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0R80_RS21710 (N0R80_21710) 460046..461261 + 1216 Protein_427 YeeE/YedE family protein -
N0R80_RS21715 (N0R80_21715) 461643..462317 + 675 WP_275600165.1 hypothetical protein -
N0R80_RS21720 (N0R80_21720) 462788..464215 + 1428 WP_275596165.1 ISNCY family transposase -
N0R80_RS21725 (N0R80_21725) 464820..465047 + 228 WP_080636789.1 CopG family transcriptional regulator Antitoxin
N0R80_RS21730 (N0R80_21730) 465044..465490 + 447 WP_275599104.1 PIN domain-containing protein Toxin
N0R80_RS21735 (N0R80_21735) 465487..466392 - 906 WP_275599103.1 LysR family transcriptional regulator -
N0R80_RS21740 (N0R80_21740) 466487..466813 + 327 WP_102763395.1 nuclear transport factor 2 family protein -
N0R80_RS21745 (N0R80_21745) 466810..467599 + 790 Protein_434 SDR family oxidoreductase -
N0R80_RS21750 (N0R80_21750) 467804..469584 + 1781 Protein_435 monovalent cation:proton antiporter-2 (CPA2) family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695765 1695765
- flank IS/Tn - - 462788..464215 1427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15668.94 Da        Isoelectric Point: 7.4219

>T257319 WP_275599104.1 NZ_CP104136:465044-465490 [Sinorhizobium sp. C101]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAATGQTAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVGKMRSLPGHSF
WPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITATRVR

Download         Length: 447 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8181.38 Da        Isoelectric Point: 7.0120

>AT257319 WP_080636789.1 NZ_CP104136:464820-465047 [Sinorhizobium sp. C101]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSSGERNGIPLLSPQPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References