Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 464820..465490 Replicon plasmid pC101b
Accession NZ_CP104136
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0R80_RS21730 Protein ID WP_275599104.1
Coordinates 465044..465490 (+) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0R80_RS21725 Protein ID WP_080636789.1
Coordinates 464820..465047 (+) Length 76 a.a.

Genomic Context

N0R80_RS21710N0R80_RS21715N0R80_RS21720N0R80_RS21725N0R80_RS21730N0R80_RS21740N0R80_RS21745N0R80_RS21750N0R80_RS21735
Location: 460046..461261 (1216 bp)
Type: Others
Protein ID: Protein_427
Location: 461643..462317 (675 bp)
Type: Others
Protein ID: WP_275600165.1
Location: 462788..464215 (1428 bp)
Type: Others
Protein ID: WP_275596165.1
Location: 464820..465047 (228 bp)
Type: Antitoxin
Protein ID: WP_080636789.1
Location: 465044..465490 (447 bp)
Type: Toxin
Protein ID: WP_275599104.1
Location: 466487..466813 (327 bp)
Type: Others
Protein ID: WP_102763395.1
Location: 466810..467599 (790 bp)
Type: Others
Protein ID: Protein_434
Location: 467804..469584 (1781 bp)
Type: Others
Protein ID: Protein_435
Location: 465487..466392 (906 bp)
Type: Others
Protein ID: WP_275599103.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
N0R80_RS21710 (N0R80_21710)460046..461261+1216Protein_427YeeE/YedE family protein-
N0R80_RS21715 (N0R80_21715)461643..462317+675WP_275600165.1hypothetical protein-
N0R80_RS21720 (N0R80_21720)462788..464215+1428WP_275596165.1ISNCY family transposase-
N0R80_RS21725 (N0R80_21725)464820..465047+228WP_080636789.1CopG family transcriptional regulatorAntitoxin
N0R80_RS21730 (N0R80_21730)465044..465490+447WP_275599104.1PIN domain-containing proteinToxin
N0R80_RS21735 (N0R80_21735)465487..466392-906WP_275599103.1LysR family transcriptional regulator-
N0R80_RS21740 (N0R80_21740)466487..466813+327WP_102763395.1nuclear transport factor 2 family protein-
N0R80_RS21745 (N0R80_21745)466810..467599+790Protein_434SDR family oxidoreductase-
N0R80_RS21750 (N0R80_21750)467804..469584+1781Protein_435monovalent cation:proton antiporter-2 (CPA2) family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid-htpB1..16957651695765
-flankIS/Tn--462788..4642151427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15668.94 Da        Isoelectric Point: 7.4219

>T257319 WP_275599104.1 NZ_CP104136:465044-465490 [Sinorhizobium sp. C101]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAATGQTAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVGKMRSLPGHSF
WPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITATRVR

Download         Length: 447 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8181.38 Da        Isoelectric Point: 7.0120

>AT257319 WP_080636789.1 NZ_CP104136:464820-465047 [Sinorhizobium sp. C101]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSSGERNGIPLLSPQPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References