257318

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 138999..139660 Replicon plasmid pC101b
Accession NZ_CP104136
Organism Sinorhizobium sp. C101

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0R80_RS20295 Protein ID WP_275599281.1
Coordinates 138999..139406 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0R80_RS20300 Protein ID WP_275599280.1
Coordinates 139406..139660 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0R80_RS20285 (N0R80_20285) 135300..137663 + 2364 WP_275600147.1 EAL domain-containing protein -
N0R80_RS20290 (N0R80_20290) 137729..138721 - 993 WP_275599282.1 inositol 2-dehydrogenase -
N0R80_RS20295 (N0R80_20295) 138999..139406 - 408 WP_275599281.1 type II toxin-antitoxin system VapC family toxin Toxin
N0R80_RS20300 (N0R80_20300) 139406..139660 - 255 WP_275599280.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N0R80_RS20305 (N0R80_20305) 139874..140116 + 243 WP_026168958.1 hypothetical protein -
N0R80_RS20310 (N0R80_20310) 140120..140572 - 453 WP_275599279.1 hypothetical protein -
N0R80_RS20315 (N0R80_20315) 140637..141616 - 980 Protein_148 LysR family transcriptional regulator -
N0R80_RS20320 (N0R80_20320) 141889..142956 + 1068 WP_100670072.1 sugar ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695765 1695765


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14939.14 Da        Isoelectric Point: 6.8818

>T257318 WP_275599281.1 NZ_CP104136:c139406-138999 [Sinorhizobium sp. C101]
MYLVDTNIVSEARRGTPQALSWLRSVDPLSIQLSALTLGEIMRGIALKQKSDPKAAAHLTEWLRKLRHDHGDRILPVTDQ
IAVEWGRIAAIRSRGDIDGLLAATAIVHDLILVTRNVRDFEDTGASVINPWETPA

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9286.46 Da        Isoelectric Point: 5.8213

>AT257318 WP_275599280.1 NZ_CP104136:c139660-139406 [Sinorhizobium sp. C101]
MDWQLQDAKNHFSKVVQKARNEGPQIVTLRGERTAVVLSARDYDALRAGRPTLVDDLLGGPPWDDELAEAIEARAKTPSR
GVAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References