Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 1493759..1494429 Replicon plasmid pK101c
Accession NZ_CP104133
Organism Sinorhizobium sp. K101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0Q91_RS30330 Protein ID WP_275599104.1
Coordinates 1493759..1494205 (-) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q91_RS30335 Protein ID WP_080636789.1
Coordinates 1494202..1494429 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q91_RS30310 (N0Q91_30335) 1489665..1491446 - 1782 WP_275599102.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
N0Q91_RS30315 (N0Q91_30340) 1491651..1492439 - 789 WP_018099177.1 SDR family oxidoreductase -
N0Q91_RS30320 (N0Q91_30345) 1492436..1492762 - 327 WP_102763395.1 nuclear transport factor 2 family protein -
N0Q91_RS30325 (N0Q91_30350) 1492857..1493762 + 906 WP_275599103.1 LysR family transcriptional regulator -
N0Q91_RS30330 (N0Q91_30355) 1493759..1494205 - 447 WP_275599104.1 PIN domain-containing protein Toxin
N0Q91_RS30335 (N0Q91_30360) 1494202..1494429 - 228 WP_080636789.1 CopG family transcriptional regulator Antitoxin
N0Q91_RS30340 (N0Q91_30365) 1495034..1496461 - 1428 WP_275596165.1 ISNCY family transposase -
N0Q91_RS30345 (N0Q91_30370) 1496928..1497605 - 678 WP_275599105.1 hypothetical protein -
N0Q91_RS30350 (N0Q91_30375) 1497987..1499201 - 1215 WP_275599106.1 YeeE/YedE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695711 1695711
- flank IS/Tn - - 1495034..1496461 1427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15668.94 Da        Isoelectric Point: 7.4219

>T257311 WP_275599104.1 NZ_CP104133:c1494205-1493759 [Sinorhizobium sp. K101]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAATGQTAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVGKMRSLPGHSF
WPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITATRVR

Download         Length: 447 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8181.38 Da        Isoelectric Point: 7.0120

>AT257311 WP_080636789.1 NZ_CP104133:c1494429-1494202 [Sinorhizobium sp. K101]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSSGERNGIPLLSPQPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References