257308

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 123868..124529 Replicon plasmid pK101c
Accession NZ_CP104133
Organism Sinorhizobium sp. K101

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q91_RS23880 Protein ID WP_275599281.1
Coordinates 124122..124529 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q91_RS23875 Protein ID WP_275599280.1
Coordinates 123868..124122 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q91_RS23855 (N0Q91_23880) 120572..121639 - 1068 WP_100670072.1 sugar ABC transporter substrate-binding protein -
N0Q91_RS23860 (N0Q91_23885) 121912..122891 + 980 Protein_108 LysR family transcriptional regulator -
N0Q91_RS23865 (N0Q91_23890) 122956..123408 + 453 WP_275599279.1 hypothetical protein -
N0Q91_RS23870 (N0Q91_23895) 123412..123654 - 243 WP_026168958.1 hypothetical protein -
N0Q91_RS23875 (N0Q91_23900) 123868..124122 + 255 WP_275599280.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N0Q91_RS23880 (N0Q91_23905) 124122..124529 + 408 WP_275599281.1 type II toxin-antitoxin system VapC family toxin Toxin
N0Q91_RS23885 (N0Q91_23910) 124807..125799 + 993 WP_275599282.1 inositol 2-dehydrogenase -
N0Q91_RS23890 (N0Q91_23915) 125865..128229 - 2365 Protein_114 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695711 1695711


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14939.14 Da        Isoelectric Point: 6.8818

>T257308 WP_275599281.1 NZ_CP104133:124122-124529 [Sinorhizobium sp. K101]
MYLVDTNIVSEARRGTPQALSWLRSVDPLSIQLSALTLGEIMRGIALKQKSDPKAAAHLTEWLRKLRHDHGDRILPVTDQ
IAVEWGRIAAIRSRGDIDGLLAATAIVHDLILVTRNVRDFEDTGASVINPWETPA

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9286.46 Da        Isoelectric Point: 5.8213

>AT257308 WP_275599280.1 NZ_CP104133:123868-124122 [Sinorhizobium sp. K101]
MDWQLQDAKNHFSKVVQKARNEGPQIVTLRGERTAVVLSARDYDALRAGRPTLVDDLLGGPPWDDELAEAIEARAKTPSR
GVAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References