257307

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 367956..368626 Replicon plasmid pK101b
Accession NZ_CP104132
Organism Sinorhizobium sp. K101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0Q91_RS21355 Protein ID WP_275598668.1
Coordinates 368207..368626 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q91_RS21350 Protein ID WP_275598667.1
Coordinates 367956..368210 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q91_RS21330 (N0Q91_21340) 364138..365073 + 936 WP_275598663.1 ABC transporter permease -
N0Q91_RS21335 (N0Q91_21345) 365079..365900 + 822 WP_275598664.1 ABC transporter permease -
N0Q91_RS21340 (N0Q91_21350) 365897..366808 + 912 WP_275598665.1 ABC transporter ATP-binding protein -
N0Q91_RS21345 (N0Q91_21355) 366805..367767 + 963 WP_275598666.1 ATP-binding cassette domain-containing protein -
N0Q91_RS21350 (N0Q91_21360) 367956..368210 + 255 WP_275598667.1 plasmid stabilization protein Antitoxin
N0Q91_RS21355 (N0Q91_21365) 368207..368626 + 420 WP_275598668.1 type II toxin-antitoxin system VapC family toxin Toxin
N0Q91_RS21360 (N0Q91_21370) 368795..369202 - 408 WP_275598669.1 GFA family protein -
N0Q91_RS21365 (N0Q91_21375) 369598..372132 + 2535 WP_275598689.1 PAS domain S-box protein -
N0Q91_RS21370 (N0Q91_21380) 372159..372521 + 363 WP_275598670.1 response regulator -
N0Q91_RS21375 (N0Q91_21385) 372604..373521 + 918 WP_275598671.1 DnaJ C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..772620 772620


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14859.15 Da        Isoelectric Point: 5.7116

>T257307 WP_275598668.1 NZ_CP104132:368207-368626 [Sinorhizobium sp. K101]
MIVLDTNVVSEVMKPAADPAVRSWLNEQVAETLYLASVTLAELLFGIGALPDGRRKKALAEMFDGVLELFGDRVLPFDIG
AARYYAGLAVTARAAGKGFPTPDGYIAAIAASRGFLVATRDISPFEAAGLTVVNPWHHR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9526.90 Da        Isoelectric Point: 6.4732

>AT257307 WP_275598667.1 NZ_CP104132:367956-368210 [Sinorhizobium sp. K101]
MAILTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRVRMGDALAELGRRLGLTNDDFAVFDEIRDKAPAQP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References