257306

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VapB
Location 240138..240718 Replicon plasmid pK101b
Accession NZ_CP104132
Organism Sinorhizobium sp. K101

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0Q91_RS20765 Protein ID WP_275598578.1
Coordinates 240335..240718 (+) Length 128 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q91_RS20760 Protein ID WP_275598577.1
Coordinates 240138..240338 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q91_RS20740 (N0Q91_20750) 235975..236772 + 798 WP_275598573.1 ABC transporter ATP-binding protein -
N0Q91_RS20745 (N0Q91_20755) 236744..237445 - 702 WP_275598574.1 class I SAM-dependent methyltransferase -
N0Q91_RS20750 (N0Q91_20760) 237810..238535 - 726 WP_275598575.1 calcium-binding protein -
N0Q91_RS20755 (N0Q91_20765) 238472..239758 - 1287 WP_275598576.1 calcium-binding protein -
N0Q91_RS20760 (N0Q91_20770) 240138..240338 + 201 WP_275598577.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
N0Q91_RS20765 (N0Q91_20775) 240335..240718 + 384 WP_275598578.1 type II toxin-antitoxin system VapC family toxin Toxin
N0Q91_RS20770 (N0Q91_20780) 240811..241200 - 390 WP_102761961.1 ester cyclase -
N0Q91_RS20775 (N0Q91_20785) 241542..241964 - 423 WP_275598579.1 type II toxin-antitoxin system VapC family toxin -
N0Q91_RS20780 (N0Q91_20790) 241961..242215 - 255 WP_275598580.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
N0Q91_RS20785 (N0Q91_20795) 242367..242987 - 621 WP_275598581.1 hypothetical protein -
N0Q91_RS20790 (N0Q91_20800) 244030..244503 - 474 WP_018096595.1 MarR family transcriptional regulator -
N0Q91_RS20795 (N0Q91_20805) 244765..245178 - 414 WP_275598582.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..772620 772620


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-113)

Antitoxin

Bacterial antitoxin of type II TA system, VapB

(1-42)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14269.53 Da        Isoelectric Point: 7.5964

>T257306 WP_275598578.1 NZ_CP104132:240335-240718 [Sinorhizobium sp. K101]
VILADTSIWIDHFRHTDAELRRIVEDDRLLCHPAVIGELALGSLRERSSVIAFLMAQREALVATHHEVMMMVDRHAIFSM
GIGYTDAHLLASVLLDKRVALWTRDKRLRAAAEKAGASLHTPAHTRN

Download         Length: 384 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7011.11 Da        Isoelectric Point: 10.7473

>AT257306 WP_275598577.1 NZ_CP104132:240138-240338 [Sinorhizobium sp. K101]
MRSTINLDDALMETAKSLTGTKETAALVRQALETLVRVESGKRLIALGGTMPDAEAAPRRRSAAAK

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References