Detailed information of TA system TA257303

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 2680782..2681458
• Replicon: plasmid pK101a
• Accession: NZ_CP104131
• Organism: Sinorhizobium sp. K101

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: N0Q91_RS15610
• Protein ID: WP_275596863.1
• Coordinates: 2680782..2681198 (-)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A2N8K0L2
• Locus tag: N0Q91_RS15615
• Protein ID: WP_018094055.1
• Coordinates: 2681195..2681458 (-)
• Length: 88 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	pgm / acpXL / kdsA / tufA / tufA / acpXL / htpB / icl / fliQ / adeG / kdsB	1..3521393	3521393

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (5-125)

Antitoxin

• SpoVT-AbrB domain (11-54)

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 15391.92 Da
• Isoelectric Point: 8.9532

>T257303 WP_275596863.1 NZ_CP104131:c2681198-2680782 [Sinorhizobium sp. K101]
MSLWMLDTKIAGHVIKGDRPEIIDRLVSLPITDIVVSSVTEGELLYGLAKRGYPRTLSERVRQFLLRVDVLPWNRTAARS
YGDLRAACEAKGAALAPLDMMIAAHAVAFDAVLVTRDRAFTRVAEPLKTDDWTDQKLK

Nucleotide

• Length: 417 bp

Antitoxin

Protein

• Length: 88 a.a.
• Molecular weight: 9846.96 Da
• Isoelectric Point: 5.1708

>AT257303 WP_018094055.1 NZ_CP104131:c2681458-2681195 [Sinorhizobium sp. K101]
VATKTAKIFASGRSQAVRLPAEFRFEGSEVFVRRDPKTGDVILSRKPDSWDGLFELYGKDQVGDDFLGPADRKQPSQDRD
PFEGWKE

Nucleotide

• Length: 264 bp

Structures

Antitoxin

• AlphaFold DB: A0A2N8K0L2