Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-Xre |
| Location | 1683282..1684214 | Replicon | plasmid pM103c |
| Accession | NZ_CP104129 | ||
| Organism | Sinorhizobium sp. M103 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | - |
| Locus tag | N0Q90_RS31270 | Protein ID | WP_275598965.1 |
| Coordinates | 1683660..1684214 (+) | Length | 185 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A2N8JW20 |
| Locus tag | N0Q90_RS31265 | Protein ID | WP_018097157.1 |
| Coordinates | 1683282..1683653 (+) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| N0Q90_RS31245 (N0Q90_31250) | 1679168..1679551 | + | 384 | WP_100670781.1 | RidA family protein | - |
| N0Q90_RS31250 (N0Q90_31255) | 1679569..1681557 | + | 1989 | WP_275602737.1 | acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha | - |
| N0Q90_RS31255 (N0Q90_31260) | 1681554..1682424 | + | 871 | Protein_1573 | hydroxymethylglutaryl-CoA lyase | - |
| N0Q90_RS31260 (N0Q90_31265) | 1682421..1683227 | + | 807 | WP_275602738.1 | crotonase/enoyl-CoA hydratase family protein | - |
| N0Q90_RS31265 (N0Q90_31270) | 1683282..1683653 | + | 372 | WP_018097157.1 | DUF2384 domain-containing protein | Antitoxin |
| N0Q90_RS31270 (N0Q90_31275) | 1683660..1684214 | + | 555 | WP_275598965.1 | RES family NAD+ phosphorylase | Toxin |
| N0Q90_RS31275 (N0Q90_31280) | 1684914..1685864 | + | 951 | WP_275598966.1 | IS110 family transposase | - |
| N0Q90_RS31280 (N0Q90_31285) | 1686174..1687538 | - | 1365 | WP_275598967.1 | FAD-binding oxidoreductase | - |
| N0Q90_RS31285 (N0Q90_31290) | 1687650..1688753 | - | 1104 | WP_275598968.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | htpB | 1..1695771 | 1695771 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 185 a.a. Molecular weight: 20341.28 Da Isoelectric Point: 6.7527
>T257298 WP_275598965.1 NZ_CP104129:1683660-1684214 [Sinorhizobium sp. M103]
MRKHSPLVSRPDPEPTASVEPITLWRAFVPRWAHMPLSGAGAARFGGRWNPIGVPAIYGARELSTAWAEYNQGFVQHPAL
IVQLELLGARLADLTDVSLLVELGVDEAIHRCEWRDALDKGAVPETHRLQSELLARDFHGVIYPSFMSPGGTCVALWRWN
GPQEPRLGVIDPDGRLPKSPASWV
MRKHSPLVSRPDPEPTASVEPITLWRAFVPRWAHMPLSGAGAARFGGRWNPIGVPAIYGARELSTAWAEYNQGFVQHPAL
IVQLELLGARLADLTDVSLLVELGVDEAIHRCEWRDALDKGAVPETHRLQSELLARDFHGVIYPSFMSPGGTCVALWRWN
GPQEPRLGVIDPDGRLPKSPASWV
Download Length: 555 bp
Antitoxin
Download Length: 124 a.a. Molecular weight: 13109.26 Da Isoelectric Point: 9.9996
>AT257298 WP_018097157.1 NZ_CP104129:1683282-1683653 [Sinorhizobium sp. M103]
MIALDFQIPAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLESVRAGVYA
MIALDFQIPAARFGDDHSPFLSARLVADRLGVTLAELAKLIGVARNTLTAKSGARKVDSALSKVVRILAMASEMAGDEAR
AVIWFKHQPIPGWAGKTAFDLVGEGKADKVLAYLESVRAGVYA
Download Length: 372 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|