257297

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 562464..563125 Replicon plasmid pM103c
Accession NZ_CP104129
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q90_RS25905 Protein ID WP_275599281.1
Coordinates 562718..563125 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q90_RS25900 Protein ID WP_275599280.1
Coordinates 562464..562718 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS25880 (N0Q90_25885) 559167..560234 - 1068 WP_100670072.1 sugar ABC transporter substrate-binding protein -
N0Q90_RS25885 (N0Q90_25890) 560507..561486 + 980 Protein_501 LysR family transcriptional regulator -
N0Q90_RS25890 (N0Q90_25895) 561551..562003 + 453 WP_275599279.1 hypothetical protein -
N0Q90_RS25895 (N0Q90_25900) 562007..562249 - 243 WP_026168958.1 hypothetical protein -
N0Q90_RS25900 (N0Q90_25905) 562464..562718 + 255 WP_275599280.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N0Q90_RS25905 (N0Q90_25910) 562718..563125 + 408 WP_275599281.1 type II toxin-antitoxin system VapC family toxin Toxin
N0Q90_RS25910 (N0Q90_25915) 563403..564395 + 993 WP_275599282.1 inositol 2-dehydrogenase -
N0Q90_RS25915 (N0Q90_25920) 564461..566824 - 2364 Protein_507 EAL domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695771 1695771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-61)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14939.14 Da        Isoelectric Point: 6.8818

>T257297 WP_275599281.1 NZ_CP104129:562718-563125 [Sinorhizobium sp. M103]
MYLVDTNIVSEARRGTPQALSWLRSVDPLSIQLSALTLGEIMRGIALKQKSDPKAAAHLTEWLRKLRHDHGDRILPVTDQ
IAVEWGRIAAIRSRGDIDGLLAATAIVHDLILVTRNVRDFEDTGASVINPWETPA

Download         Length: 408 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9286.46 Da        Isoelectric Point: 5.8213

>AT257297 WP_275599280.1 NZ_CP104129:562464-562718 [Sinorhizobium sp. M103]
MDWQLQDAKNHFSKVVQKARNEGPQIVTLRGERTAVVLSARDYDALRAGRPTLVDDLLGGPPWDDELAEAIEARAKTPSR
GVAF

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References