257296

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 236622..237292 Replicon plasmid pM103c
Accession NZ_CP104129
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0Q90_RS24455 Protein ID WP_275599104.1
Coordinates 236622..237068 (-) Length 149 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q90_RS24460 Protein ID WP_080636789.1
Coordinates 237065..237292 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS24435 (N0Q90_24440) 232528..234309 - 1782 WP_275599102.1 monovalent cation:proton antiporter-2 (CPA2) family protein -
N0Q90_RS24440 (N0Q90_24445) 234514..235302 - 789 WP_018099177.1 SDR family oxidoreductase -
N0Q90_RS24445 (N0Q90_24450) 235299..235625 - 327 WP_102763395.1 nuclear transport factor 2 family protein -
N0Q90_RS24450 (N0Q90_24455) 235720..236625 + 906 WP_275599103.1 LysR family transcriptional regulator -
N0Q90_RS24455 (N0Q90_24460) 236622..237068 - 447 WP_275599104.1 PIN domain-containing protein Toxin
N0Q90_RS24460 (N0Q90_24465) 237065..237292 - 228 WP_080636789.1 CopG family transcriptional regulator Antitoxin
N0Q90_RS24465 (N0Q90_24470) 237897..239324 - 1428 WP_275596165.1 ISNCY family transposase -
N0Q90_RS24470 (N0Q90_24475) 239791..240468 - 678 WP_275599105.1 hypothetical protein -
N0Q90_RS24475 (N0Q90_24480) 240850..242065 - 1216 Protein_219 YeeE/YedE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695771 1695771
- flank IS/Tn - - 237897..239324 1427


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-131)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 149 a.a.        Molecular weight: 15668.94 Da        Isoelectric Point: 7.4219

>T257296 WP_275599104.1 NZ_CP104129:c237068-236622 [Sinorhizobium sp. M103]
VTFLLDVNVLIALIDPGHVAHDDAHEWFAATGQTAWATCPITENGVIRIVGNPKYPNSPGSPSLVMEIVGKMRSLPGHSF
WPDDVSLVGSGDIAPTKILTSGQVTDTYLLALAKARGGQLATFDRKLSAAAVTRGNSALHLITATRVR

Download         Length: 447 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8181.38 Da        Isoelectric Point: 7.0120

>AT257296 WP_080636789.1 NZ_CP104129:c237292-237065 [Sinorhizobium sp. M103]
MRTTLAIDDDVLIAAKAMAAQQHRSVGEVISELARRSLRRPRSSGERNGIPLLSPQPDAPPVTLEIVNALRDELP

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References