257295

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 138228..139035 Replicon plasmid pM103c
Accession NZ_CP104129
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag N0Q90_RS23990 Protein ID WP_100670374.1
Coordinates 138228..138752 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID A0A2N8JWE8
Locus tag N0Q90_RS23995 Protein ID WP_018097027.1
Coordinates 138745..139035 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS23965 (N0Q90_23970) 133328..134185 + 858 WP_100670384.1 carbohydrate ABC transporter permease -
N0Q90_RS23970 (N0Q90_23975) 134214..135442 + 1229 Protein_118 extracellular solute-binding protein -
N0Q90_RS23975 (N0Q90_23980) 135531..136661 + 1131 WP_275599049.1 sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC -
N0Q90_RS23980 (N0Q90_23985) 136664..137164 + 501 WP_275599050.1 GNAT family N-acetyltransferase -
N0Q90_RS23985 (N0Q90_23990) 137312..137695 + 384 WP_102762399.1 VOC family protein -
N0Q90_RS23990 (N0Q90_23995) 138228..138752 - 525 WP_100670374.1 GNAT family N-acetyltransferase Toxin
N0Q90_RS23995 (N0Q90_24000) 138745..139035 - 291 WP_018097027.1 DUF1778 domain-containing protein Antitoxin
N0Q90_RS24000 (N0Q90_24005) 139178..139435 - 258 WP_018097026.1 hypothetical protein -
N0Q90_RS24005 (N0Q90_24010) 139455..140030 - 576 WP_275599051.1 thermonuclease family protein -
N0Q90_RS24010 (N0Q90_24015) 140405..141889 - 1485 WP_275602749.1 succinoglycan biosynthesis transport protein ExoT -
N0Q90_RS24015 (N0Q90_24020) 142013..142970 + 958 Protein_127 succinoglycan biosynthesis glycosyltransferase ExoW -
N0Q90_RS24020 (N0Q90_24025) 143085..144035 + 951 WP_275599053.1 succinoglycan biosynthesis protein ExoV -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..1695771 1695771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(2-88)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 18532.30 Da        Isoelectric Point: 7.3207

>T257295 WP_100670374.1 NZ_CP104129:c138752-138228 [Sinorhizobium sp. M103]
VLDWREEPIGRHHDRKAFDCGTPELNEYLRRHARQNHEGGGSKTFVAVAPTAPETILGYYSISPASIAFAKVPAPLTKGL
GRYEVAVYRLARLAVALPLQGRGLGGDLLLAAGARALAVAAQVGGVALAIDAKDEKAACWYERFGAMPLLDSSPLSLILP
FKTIIDALDAAQGE

Download         Length: 525 bp

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10730.29 Da        Isoelectric Point: 10.6264

>AT257295 WP_018097027.1 NZ_CP104129:c139035-138745 [Sinorhizobium sp. M103]
MAQMQANRDDRIELRTTRDEKRLLTAAAAHERLDVTSFIMRAVLPAAREVVENAERISLSERDSLRVLDLLENPPAPTPA
LLAAARRRIARDGKSA

Download         Length: 291 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A2N8JWE8

References