Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 587569..588239 Replicon plasmid pM103b
Accession NZ_CP104128
Organism Sinorhizobium sp. M103

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag N0Q90_RS22485 Protein ID WP_275598668.1
Coordinates 587820..588239 (+) Length 140 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag N0Q90_RS22480 Protein ID WP_275598667.1
Coordinates 587569..587823 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N0Q90_RS22460 (N0Q90_22465) 583751..584686 + 936 WP_275598663.1 ABC transporter permease -
N0Q90_RS22465 (N0Q90_22470) 584692..585513 + 822 WP_275598664.1 ABC transporter permease -
N0Q90_RS22470 (N0Q90_22475) 585510..586421 + 912 WP_275598665.1 ABC transporter ATP-binding protein -
N0Q90_RS22475 (N0Q90_22480) 586418..587380 + 963 WP_275598666.1 ATP-binding cassette domain-containing protein -
N0Q90_RS22480 (N0Q90_22485) 587569..587823 + 255 WP_275598667.1 plasmid stabilization protein Antitoxin
N0Q90_RS22485 (N0Q90_22490) 587820..588239 + 420 WP_275598668.1 type II toxin-antitoxin system VapC family toxin Toxin
N0Q90_RS22490 (N0Q90_22495) 588408..588815 - 408 WP_275598669.1 GFA family protein -
N0Q90_RS22495 (N0Q90_22500) 589211..591745 + 2535 WP_275598689.1 PAS domain S-box protein -
N0Q90_RS22500 (N0Q90_22505) 591772..592134 + 363 WP_275598670.1 response regulator -
N0Q90_RS22505 (N0Q90_22510) 592217..593134 + 918 WP_275598671.1 DnaJ C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..772647 772647


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 14859.15 Da        Isoelectric Point: 5.7116

>T257294 WP_275598668.1 NZ_CP104128:587820-588239 [Sinorhizobium sp. M103]
MIVLDTNVVSEVMKPAADPAVRSWLNEQVAETLYLASVTLAELLFGIGALPDGRRKKALAEMFDGVLELFGDRVLPFDIG
AARYYAGLAVTARAAGKGFPTPDGYIAAIAASRGFLVATRDISPFEAAGLTVVNPWHHR

Download         Length: 420 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9526.90 Da        Isoelectric Point: 6.4732

>AT257294 WP_275598667.1 NZ_CP104128:587569-587823 [Sinorhizobium sp. M103]
MAILTVRNVPDEVHRALRVRAAMHGRSTEAEVREILESAVKPEQRVRMGDALAELGRRLGLTNDDFAVFDEIRDKAPAQP
MRFE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References